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| Effect of Galium verum L. Solution combined with acupuncture and moxibustion therapy on chronic skin ulcer of lower limbs |
| YUAN Haigang1,2 ZHAO Gang2 JIA Zhen2 LYU Bochuan2 HUANG Yanhong2 ZHANG Bailiang2 JIANG Deyou2 WANG Xuejun1 |
1.Heilongjiang Academy of Chinese Medicine, Heilongjiang Province, Harbin 150036, China;
2.Department of Peripheral Vascular Disease, the First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150040, China |
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Abstract Objective To research the effect of Galium verum L. Solution combined with acupuncture and moxibustion therapy on chronic skin ulcer of lower limbs. Methods From January to May 2019, eighty-six patients with chronic skin ulcer of lower limbs who met the experimental criteria were selected from the Department of Peripheral Vascular Diseases, the First Affiliated Hospital of Heilongjiang University of Chinese Medicine, they were divided into experimental group and control group by using random number table method, with 43 cases in both group. Two groups were active in the treatment of primary diseases, while the debridement and dressing change were needed daily. Galium verum L. Solution was sprayed on the ulcer surface in the experimental group. At the same time, multiple acupuncture points of affected limbs were selected and moxibustion was carried out once a day. The patients in the control group were sprayed with Benazine solution on the ulcer surface. Two groups were treated continuously for four weeks. At the beginning and end of the experiment, the ulcer area was calculated by a sterile transparent biofilm method, and the ulcer healing of the two groups was compared. The healing time of ulcer after treatment was recorded and compared between the two groups. The numbers of patients at all levels after treatment in the two groups were recorded according to the evaluation criteria of wound granulation tissue changes. The changes of wound granulation tissue were compared. Results In the experimental group, the total effective rate was higher than that in control group, and the changes of new granulation tissue after treatment were significantly higher than those in the control group, while the healing time of the experimental group was significantly shorter than that in the control group, and the differences were statistically significant (P ＜ 0.05). Conclusion The clinical effect of Galium verum L. Solution combined with acupuncture and moxibustion therapy on chronic skin ulcer of lower limbs is significant and better than that of Benazine solution. It is worthy of clinical application.
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