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| The correlation study of MSCT and pulmonary function in patients of chronic obstructive pulmonary disease combined with bronchiectasis |
| LIANG Kaiyi1 YU Yanfang2 ZHOU Hui1 |
1.Department of Radiology, Shanghai Jiading District Central Hospital, Shanghai 201800, China;
2.Department of Respiration, Shanghai Jiading District Central Hospital, Shanghai 201800, China |
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Abstract Objective To explore the correlation between lung volume index of multi-slice spiral CT (MSCT) and routine pulmonary function of patients suffering from chronic obstructive pulmonary disease (COPD) combined with bronchiectasis. Methods From January 2015 to December 2016, a total of 104 hospitalized patients in Department of Respiration, Shanghai Jiading District Central Hospital were selected and divided into COPD group(56 cases) and COPD combined with bronchiectasis (48 cases) by whether combined with bronchiectasis. The lung volume indexes of MSCT and routine pulmonary function were compared between the two groups. The correlation of lung volume indexes of MSCT and routine pulmonary function in the group of COPD combined with bronchiectasis were analyzed. Results FEV1%pred, FEV1/FVC, FVC%pred, DLCO%pred in the COPD combined with bronchiectasis group were lower than those of COPD group, and RV/TLC was significantly higher than that of COPD group(P ＜ 0.01). The lung volume indexes of inspiratory volume (Vin), expiratory volume （Vex), Vex/Vin in the COPD combined with bronchiectasis group were all higher than those of COPD group(P ＜ 0.05), and the Vin-Vex was much lower than that of COPD group(P ＜ 0.05). The lung volume indexes of Vin in the COPD combined with bronchiectasis group in MSCT was negatively correlated with the lung volume indexes of FEV1 and FEV1/FVC(r ＜ 0，P ＜ 0.05), and the Vin was positively correlated with the lung volume indexes of RV, TLC and RV/TLC (r ＞ 0，P ＜ 0.05). Vex was negatively correlated with the lung volume indexes of FEV1, FEV1/FVC, TLC and RV/TLC (r ＜ 0，P ＜ 0.05), Vex was positively correlated with RV(r ＞ 0，P ＜ 0.05); Vex/Vin was negatively correlated with FEV1, TLC and RV/TLC(r ＜ 0，P ＜ 0.05); and was positivily correlated with RV.Vin-Vex/Vin was positively correlated with FEV1, FEV1/FVC, RV, TLC and RV/TLC(r ＞ 0，P ＜ 0.05). Conclusion The pulmonary function of COPD patients combined with bronchiectasis declined more apparently and indicates the condition is more serious. The pulmonary function and changes in the bronchi structure of COPD patients combined with bronchiectasis can be clarified by MSCT and it has great significance for the diagnostic, treatment and prognostic evaluation.
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