|
|
|
| Severe hypokalemia complicated with rhabdomyolysis due to chronic diarrhea in an elderly patient |
| HE Ke LIU Ling BIAN Rongrong LU Xiwan ZHU Lihua |
| Department of Endocrinology, Wuxi Hospital of Traditional Chinese Medicine (Wuxi Hospital Affiliated to Nanjing University of Chinese Medicine), Jiangsu Province, Wuxi 214000, China |
|
|
|
Abstract The etiology of hypokalaemia is a common clinical electrolyte disorder, which is complex and the clinical manifestations are diverse. The complication of rhabdomyolysis is prone to delayed diagnosis or missed diagnosis, thus affecting the prognosis. This paper reported a case of severe hypokalemia combined with rhabdomyolysis caused by chronic diarrhea in an elderly patient in Wuxi Hospital of Traditional Chinese Medicine, whose minimum potassium at 1.45 mmol/L, and rised levels of serum creatine kinase (CK), creatine kinase MB (CK-MB). After complementing potassium, hydration, diuresis, antioxidation and stabilizing cell membrane, a total of 72 g potassium chloride was supplied, then potassium returned to normal, and levels of CK, CK-MB gradually returned to stable. The purpose of this paper is to summarize the experiences of this kind of disease and give a guidance for diagnose and treatment in hypokalemia combined with rhabdomyolysis.
|
|
|
|
|
|
[1] He R，Guo WJ，She F，et al. A rare case of hypokalemia-induced rhabdomyolysis [J]. J Geriatr Cardiol，2018，15（4）：321-324.
[2] Cohn JN，Kowey PR，Whelton PK. New guidelines for potassium replacement in clinical practice：a contemporary review by the National Council on Potassium in Clinical Practice [J]. Arch Intern Med，2000，160（16）：2429-2436.
[3] Santos I，Alves Teixeira J，Costa C. Bidirectional ventricular tachycardia due to hypokalaemia [J]. BMJ Case Rep，2018，11（1）.pii: e228195. doi：10.1136/bcr-2018-228195.
[4] Du Y，Mou Y. Efficiency evaluation and safety monitoring of tailored rapid potassium supplementation strategy for fatal severe hypokalemia [J]. Expe Ther Med，2019，17（4）：3222-3232.
[5] Cervellin G，Comelli I，Lippi G. Rhabdomyolysis：historical background，clinical，diagnostic and therapeutic features [J]. Clin Chem Lab Med，2010，48（6）：749-756．
[6] Wongrakpanich S，Kallis C，Prasad P，et al. Prevalence of false positive troponin I in elderly patients with rhabdomyolysis [J]. Geriatr Gerontol Int，2017，17（7）：1137-1140．
[7] 余武，李敬会，徐剑刚.重度低钾血症致横纹肌溶解症1例[J].中国老年学杂志，2014，34（21）：6204-6206.
[8] 陈灏珠.实用内科学[M].12版.北京：人民卫生出版社，2005：984-986，2730-2732.
[9] Martinez JJ，Oliveira CL，Meneses AL，et al. Rhabdomyolysis due to primary hyperaldosteronism [J]. Endocrinol Nutr，2009，56（8）：431-434.
[10] Patoulias D，Michailidis T，Papatolios T，et al. Rhabdomyolysis Induced by Coadministration of Fusidic Acid and Atorvastatin：A Case Report and Comprehensive Review of the Literature [J]. Case Rep NepHrol，2017，2017：2187264. doi：10.1155/2017/2187264
[11] Russell TA. Acute renal failure related to rhabdomyolysis：pathopHysiology，diagnosis，and collaborative management [J]. Nep Hrol Nurs J，2005，32（4）：409-417.
[12] Patil S，Subramany S，Patil S，et al. Ibuprofen Abuse-A Case of Rhabdomyolysis，Hypokalemia，and HypopHospHatemia With Drug-Induced Mixed Renal Tubular Acidosis [J]. Null，2018，3（5）：1237-1238.
[13] Pecnik P，Müller P，Vrabel S. Two cases of hypokalaemic rhabdomyolysis：same but different [J]. BMJ Case Rep，2018，2018. doi：10.1136/bcr-2017-223609.
[14] Jung YL. Rhabdomyolysis following severe hypokalemia caused by familial hypokalemic periodic paralysis [J]. World J Clin Cases，2017，5（2）：56-60.
[15] Shapiro ML，Baldea A，Luchette FA. Rhabdomyolysis in the intensive care unit [J]. J Intensive Care Med，2012， 27（6）：335-342.
[16] Nance JR，Mammen AL. Diagnostic evaluation of rhabdomyolysis [J]. Muscle Nerve，2015，51（6）：793-810.
[17] Zavatto A，Concistrè A，Marinelli C，et al. Hypokalemic rhabdomyolysis：a rare manifestation of primary aldosteronism [J]. Eur Rev Med Pharmacol Sci，2015，19（20）：3910-3916.
[18] Liew ZH. Liquorice-Induced Severe Hypokalaemic Rhabdomyolysis with Acute Kidney Injury [J]. Ann Acad Med Singapore，2017，46（9）：354-355.
[19] Bosch X，Poch E，Grau JM. Rhabdomyolysis and acute kidney injury [J]. N Engl J Med，2009，361（1）：62-72.
[20] Grifoni E，Fabbri A，Ciuti G，et al. Hypokalemia-induced rhabdomyolysis [J]. Inter Emerg Med，2014，9（4）：487-488. |
|
|
|
