桂枝茯苓胶囊联合地屈孕酮治疗超声子宫内膜回声欠均的异常子宫出血的临床效果

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Abstract Objective To study the clinical effect of Guizhi Fuling Capsules combined with desdrogesterone in the treatment of endometrial uneven echo detected by transvaginal ultrasound. Methods From January to October 2018, 60 cases of abnormal uterine bleeding with endometrial uneven echo by ultrasound within 10 days of menstruation were collected in the Department of Gynecology of Xiyuan Hospital, Chinese Academy of Traditional Chinese Medicine. According to their actual medication method, they were divided into observation group and control group, 30 cases in each group. The control group was treated with Dydrogesterone only in the second half of menstruation (from 15th to 25th day), while the observation group was treated with Dydrogesterone in the second half cycle (the same as the control group) and Guizhi Fuling Capsules on the 20th day of menstruation for 11 days. The clinical effects and adverse reactions of the two groups were recorded. Results After 3 months of treatment, the thickness of endometrium, rate of slightly higher echo in uterine cavity and the uneven rate of endometrial echo in both groups decreased significantly compared with before treatment, the differences were statistically significant (P < 0.05 or P < 0.01); the thickness of endometrium in observation group was lower than that of the control group, the difference was statistically significant (P < 0.05); There were no statistically significant differences in the rate of slightly higher echo in uterine cavity and the uneven rate of endometrial echo between the two groups (P > 0.05). There was no obvious adverse reactions occurred in the two groups. Conclusion Guizhi Fuling Capsules combined with Dydrogesterone in the treatment of endometrial uneven echo by ultrasound can improve the clinical efficacy and abnormal uterine bleeding, without increasing the incidence of adverse reactions, which is safe and reliable.

Key words： Guizhi Fuling Capsules Dydrogesterone Abnormal uterine bleeding Endometrial polyps

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	SUN Jiaqi ZHU Fuli HUANG Yuxiao▲

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SUN Jiaqi ZHU Fuli HUANG Yuxiao▲. Clinical effect of Guizhi Fuling Capsules combined with Didrogesterone in the treatment of abnormal uterine bleeding with endometrial uneven echo[J]. 中国医药导报, 2019, 16(24): 103-106.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2019/V16/I24/103

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