|
|
|
| Effect of different oxygen concentrations on brain damage in neonatal asphyxiation recovery |
| GU Yufang ZENG Guixiang MENG Li HUANG Chunyu JIANG Ningning |
| Department of Pediatrics, the Sixth People's Hospital of Nanning City, Guangxi Zhuang Autonomous Region, Nanning 530003, China |
|
|
|
|
Abstract Objective To discuss the clinical effects of different oxygen concentrations during neonatal asphyxiation recovery. Methods 120 full-term newborns with asphyxia treated in the Sixth People's Hospital of Nanning City from February 2016 to February 2017 were selected. The newborns were randomly divided into the air resuscitation group, low concentration oxygen group and high concentration oxygen group, each group had 40 cases. The air resuscitation group was treated with air resuscitation, high concentration oxygen group was treated with 100% oxygen resuscitation, and low concentration oxygen group was treated with 30% oxygen resuscitation. The time of began to cry and spontaneous breathing establishment, Apgar scores at different time after birth, recovery success rate and recovery safety of the three groups were compared. Results There were statistically significant differences in the time of began to cry and the time of spontaneous breathing establishment among the three groups (P < 0.05), of which the air resuscitation group and low concentration oxygen group were all shorter than the high concentration oxygen group, with statistically significant differences (P < 0.05), the low concentration oxygen group were shorter than the air resuscitation group, but no statistically significant differences (P > 0.05). There were statistically significant differences in Apgar scores at different time after birth among the three groups (P < 0.05), of which the air resuscitation group and low concentration oxygen group were higher than the high concentration oxygen group, with statistically significant differences (P < 0.05), the low concentration oxygen group were higher than the air resuscitation group, but no statistically significant differences (P > 0.05). The incidence of neonatal brain injury of the air resuscitation group and low concentration oxygen group were lower than those of the high concentration oxygen group, with statistically significant differences (P < 0.05), while the low concentration oxygen group was lower than the air resuscitation group, but no statistically significant difference (P > 0.05). The successful rate of recovery was 100.00% in three groups. The incidence of oxygen poisoning of the air resuscitation group and low concentration oxygen group were lower than those of the high concentration oxygen group, with statistically significant differences (P < 0.05), while the low concentration oxygen group was lower than the air resuscitation group, but no statistically significant difference (P > 0.05). Conclusion During the course of neonatal asphyxia resuscitation, 30% oxygen resuscitation is effective, which can achieve better recovery effect, effectively reduce brain damage and avoid the emergence of oxygen poisoning. It is a more safe and effective recovery program.
|
|
|
|
|
|
[1] 新生儿窒息多器官损害临床诊断多中心研究协作组.新生儿窒息多器官损害发生率、高危因素和转归的多中心研究[J].中华围产医学杂志，2016，19（1）：23-28.
[2] 陆健华，罗秀金.略谈新生儿窒息复苏后的护理[J].医学信息：下旬刊，2009，1（11）：172-173.
[3] 卢慧琴，赵秀敏，李香娟，等.新生儿窒息空气复苏技术在基层医院的应用及评估[J].中国妇幼保健，2014，29（15）：2443-2445.
[4] 冯娟，李秋兰.产科新生儿窒息复苏抢救管理临床模式研究[J].中国急救医学，2015，35（z2）：232-233.
[5] 齐宇洁，刘红，吴海兰，等.新生儿窒息复苏后发生持续肺动脉高压的相关因素分析[J].中华实用儿科临床杂志，2014，29（15）：1177-1179.
[6] 吴小玲.不同的氧浓度在新生儿窒息抢救中的应用[J].深圳中西医结合杂志，2015，25（4）：21-22.
[7] 卢慧琴，赵秀敏，李香娟，等.空气与纯氧复苏患儿12个月体格发育及智力发育的随访研究[J].中国妇幼保健，2014，29（28）：4570-4571.
[8] 张旭，杨梅，邱菊，等.纯氧和空气复苏患儿24个月随访观察[J].中国优生优育，2010，16（2）：86-88.
[9] Andreasen S，Backe B，?覫ian P. Claims for compensation after alleged birth asphyxia： a nationwide study covering 15 years [J]. Acta Obstetricia Et Gynecologica Scandinavica，2014，93（2）：152-158.
[10] 叶鸿瑁.继续深入开展我国的新生儿窒息复苏工作，降低新生儿窒息的病死率和伤残率[J].中华围产医学杂志，2011，14（3）：129-131.
[11] 陈志芳，吴红荷，罗晓平，等.助产士窒息复苏培训对新生儿窒息率及复苏成功率的影响[J].中国实用护理杂志，2012，28（9）：75-76.
[12] 王大中.加强产儿科医师合作对提高新生儿窒息复苏成功率的探讨[J].中国社区医师：医学专业，2012，14（1）：165.
[13] 吴艳，张立足，赵彩云，等.浅谈新生儿窒息的抢救及护理[J].中国伤残医学，2015，23（2）：238-239.
[14] 中华医学会围产医学分会新生儿复苏学组.新生儿窒息诊断的专家共识[J].中华围产医学杂志，2016，19（1）：3-6.
[15] Ersdal HL，Mduma E，Svensen E，et al. Intermittent detection of fetal heart rate abnormalities identify infants at greatest risk for fresh stillbirths，birth asphyxia，neonatal resuscitation，and early neonatal deaths in a limited-resource setting：a prospective descriptive observational study [J]. Neonatology，2012，102（3）：235-242.
[16] 梁道琼.空气和纯氧复苏方案在新生儿窒息中的应用价值比较[J].海南医学，2014，25（9）：1295-1297.
[17] 余章斌，沙莉，韩树萍，等.不同浓度氧气复苏窒息极早产儿的系统评价[J].中国新生儿科杂志，2011，26（5）：343-348.
[18] 梁明姬，马国哲，韩芳，等.足月新生儿窒息时复苏采用氧浓度与脑损伤的相关性[J].热带医学杂志，2016，16（8）：1033-1036.
[19] 刘婷婷.早产儿喉罩复苏的临床随机对照研究[D].广州：南方医科大学，2013.
[20] 谢冠浓，胡碧环，倪明军，等.窒息极早产儿采用不同氧浓度的复苏效果评价[J].临床医学工程，2016，23（6）：761-762. |
|
|
|
