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| Research progress of Chikungunya viruses |
| CHENG Meihui TAO Yufen LIU Jiansheng LIU Hongqi▲ |
| Infection and Immunity Laboratory, Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Province, Kunming 650118, China |
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Abstract Chikungunya virus (CHIKV) is an insect-borne virus transmitted by Aedes aegypti and Aedes albopictus. It has a high infection rate and can cause arthritis symptoms lasting from months to years. In severe cases, it can cause disability and even death. CHIKV has spread worldwide in recent years, infecting millions of people each year. This review introduces CHIKV from the aspects of clinical symptoms, pathological mechanism and diagnostic methods, among which, the pathological mechanism of CHIKV infection is the key part described. Understanding the pathological mechanism of CHIKV infection will be beneficial to finding methods of prevention and treatment to fight against this arbovirus.
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