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| Research progress of analysis of volatile organic compounds in biological fluids |
| TONG Hongshuang1 WANG Changsong2 |
1.Department of Anesthesiology, the First Affiliated Hospital of Harbin Medical University, Heilongjiang Province, Harbin 150000, China;
2.Department of Critical Care Medicine, Cancer Hospital Affiliated to Harbin Medical University, Heilongjiang Province, Harbin 150040, China |
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Abstract Analysis of volatile organic compounds in exhaled breath, blood, sweat, urine, saliva, pleural effusion, cerebrospinal fluid, stool is a new method that was used for the assessment of health status, disease screening and diagnosis. In recent years, this method has the advantages of non-invasive, rapid, convenient operation, cheap and patients with good tolerance. The analysis of volatile organic compounds has attracted more and more attention of researchers and expanded a new research field. At present, the metabolomics research of lung cancer in exhaled breath, blood and urine show that alkanes, aromatic hydrocarbons, oxy-compound has a certain diagnostic value. There is also a link between identified various types of cancer and some special volatile organic compounds.
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