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| Analysis of quality of life in patients with advanced ovarian cancer based on WHOQOL-BREF scale |
| LI Lin1,2 MA Hongmei1▲ ZHOU Quan2 |
1.Department of Geriatrics, Renmin Hospital of Wuhan University, Hubei Province, Wuhan 430060, China;
2.Department of Gynecology and Obstetrics, People′s Hospital of China Three Geoges University, Hubei Province, Yichang 443000, China |
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Abstract Objective To explore the quality of life and it′s influencing factors in patients with ovarian cancer. Methods From January 2017 to October 2018, in Wuhan University People′s Hospital, 86 patients with ovarian cancer were selected. The World Health Organization Quality of Life-BREF (WHOQOL-BREF) scale was used to conduct a questionnaire survey on the quality of life of the patients, and applied multiple stepwise regression methods was used to analyze the influencing factors of quality of life. Results The total life quality score in 86 cases was (58.17±13.22) scores. Scores in physiology domain was (17.73±2.99) scores, (16.23±4.20) scores in psychological domain, and (17.13±3.00) scores in environment. The multivariate Logistic regression results indicate that independent factors affecting the quality of life of ovarian cancer include: lower degree (OR = 0.604, 95%CI: 0.305-0.925), family monthly income ≤3000 yuan (OR = 2.506, 95%CI: 1.214-10.841), self-funded (OR = 2.577, 95%CI: 1.396-6.937), and a large number of symptom groups (OR = 4.578, 95%CI: 1.138-18.153). Conclusion The overall quality of life of patients with ovarian cancer is low, and it is affected by factors such as academic qualifications, medical expenses, family monthly income, and number of symptom groups.
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[1] Siegel RL，Miller KD，Jemal A. Cancer Statistics，2017 [J]. CA Cancer J Clin，2017，67（1）：7-30.
[2] Zhou Q，Hong L，Zuo MZ，et al. Prognostic significance of neutrophil to lymphocyte ratio in ovarian cancer： evidence from 4，910 patients [J]. Oncotarget，2017，8（40）：68938-68949.
[3] 甘晓晶，余莹莹.CT和MRI对卵巢癌的诊断价值比较[J].影像研究与医学应用，2018，2（1）：78-80.
[4] 陈少蕾.卵巢癌患者症状群及其生命质量的调查研究[D].济南：山东大学，2013.
[5] 张杨.对症支持护理对晚期卵巢癌患者心理状态及生命质量的影响[J].医学理论与实践，2018，31（2）：297-298.
[6] 申旭波，刘方苇，熊世敏，等.基于WHOQOL-BREF量表的中老年男性生命质量现况分析[J].现代预防医学，2018， 45（6）：1118-1121.
[7] 陈萌.类风湿关节炎患者的生命质量评价及影响因素分析[D].沈阳：中国医科大学，2018.
[8] 王阳，安力彬.卵巢癌病人症状群及其生命质量的调查研究[J].护理研究，2015，29（3）：367-368.
[9] Skevington SM，Lotfy M，O′Connell KA. The World Health Organization′s WHOQOL-BREF quality of life assessment： Psychometric properties and results of the international field trial. A Report from the WHOQOL Group [J]. Qual Life Res，2004，13（2）：299-310.
[10] 李佳佳.卵巢癌患者生命质量评估[D].长春：吉林大学，2014.
[11] 万丹丹，杨宏英，万崇华，等.卵巢癌患者生命质量及其影响因素分析[J].中国慢性病预防与控制，2013，21（2）： 129-132.
[12] 安力彬，王阳，李文涛.心理干预对卵巢癌患者生存质量影响的Meta分析[J].解放军护理杂志，2017，34（20）： 1-5.
[13] Senthil M. Assessment of clinical benefit and quality of life in patients undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for management of peritoneal carcinomatosis [J]. J Gastrointest Oncol，2013，4（1）：3-4.
[14] 霍丹，刘勇.晚期癌症患者症状群的调查分析[J].实用医学杂志，2011，27（22）：4153-4155.
[15] 黄海桃，陈珊娜，朱薪，等.卵巢癌患者化疗期间不同时间点症状群的变化规律及其与生命质量的关系[J].中国肿瘤临床与康复，2016，23（4）：502-505.
[16] 廖洁容，孟琼，杨铮，等.基于QLICP-OV量表的卵巢癌患者生活质量影响因素分析[J].重庆医学，2016，45（27）： 3773-3776.
[17] Bauersfeld SP，Kessler CS，Wischnewsky M，et al. The effects of short-term fasting on quality of life and tolerance to chemotherapy in patients with breast and ovarian cancer： a randomized cross-over pilot study [J]. BMC Cancer，2018，18（1）：476.
[18] Bonhof CS，Mols F，Vos MC，et al. Course of chemotherapy-induced peripheral neuropathy and its impact on health-related quality of life among ovarian cancer patients： A longitudinal study [J]. Gynecol Oncol，2018， 149（3）：455-463.
[19] Colombo N ，Lorusso D ，Scollo P. Impact of recurrence of ovarian cancer on quality of life and outlook for the future [J]. Int J Gynecol Cancer，2017，27（6）：1134-1140.
[20] 张研，张亮.健康中国背景下医疗保障制度向健康保障制度转型探索[J].中国卫生政策研究，2018，11（1）：2-5. |
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