|
|
|
| Effect of lumbar spine massage combined with Sodium Hyaluronate in the treatment of knee osteoarthritis |
| LI Xiaoming1 CUI Xinjie2 LI Zengtu1 |
1.Massage Department, the Third Affiliated Hospital of Zhejiang Chinese Medical University, Zhejiang Province, Hangzhou 310000, China;
2.Basic Medical College, Zhejiang Chinese Medical University, Zhejiang Province, Hangzhou 310000, China |
|
|
|
Abstract Objective To analyze the clinical efficacy of lumbar spine massage combined with Sodium Hyaluronate in the treatment of knee osteoarthritis (KOA) and its influence on serum S100A12 and cartilage oligomeric matrix protein (COMP) levels. Methods One hundred cases of KOA patients admitted to the Third Affiliated Hospital of Zhejiang Chinese Medical University from January 2016 to January 2018 were divided into the observation group and the control group by random envelope method, with 50 cases in each group. The control group was treated with Sodium Hyaluronate, while the observation group was treated with lumbar spine massage combined with Sodium Hyaluronate. After treatment, the visual analogue scale (VAS), clinical efficacy, S100A12 and COMP levels of the two groups were observed, and the satisfaction rates of the two groups were analyzed. Results After treatment, the total effective rate of observation group was significantly higher than that of control group (P ＜ 0.05). After treatment, the VAS scores of the two groups were significantly lower than those before treatment (P ＜ 0.05), and the VAS score of the observation group was significantly lower than that of control group (P ＜ 0.05). After treatment, the levels of S100A12 and COMP in the blood of the two groups were decreased significantly (P ＜ 0.05), which of observation group were significantly lower than those of control group (P ＜ 0.05). The satisfaction rate of observation group was significantly higher than that of control group (P ＜ 0.05). Conclusion The combination of lumbar spine massage and Sodium Hyaluronate in the treatment of KOA patients can improve the clinical efficacy and clinical satisfaction rate, reduce the patients′ VAS scores, S100A12 and COMP levels.
|
|
|
|
|
|
[1] Shahidi B，Hubbard JC，Gibbons MC，et al. Lumbar multifidus muscle degenerates in individuals with chronic degenerative lumbar spine pathology [J]. J Orthop Res，2017， 35（12）：2700.
[2] 邵玉霞，梅轶芳，张志毅.运动疗法在膝骨关节炎治疗中的研究进展[J].中华内科杂志，2017，56（2）：147-149.
[3] Tiouririne M，Dixon AJ，Jr MF，et al. Imaging Performance of a Handheld Ultrasound System With Real-Time Computer-Aided Detection of Lumbar Spine Anatomy：A Feasibility Study [J]. Invest Radiol，2017，52（8）：447-455.
[4] 袁学峰，任珩，刘雅静，等.补肾中药联合透明质酸钠治疗膝关节骨性关节炎疗效及对超敏C反应蛋白和炎症细胞因子的影响[J].现代中西医结合杂志，2018，27（7）：775-778.
[5] 国家中医药管理局.中医病证诊断疗效标准[M].南京：南京大学出版社，1994.
[6] Bousquet PJ，Combescure C，Klossek JM，et al. Change in visual analog scale score in a pragmatic randomized cluster trial of allergic rhinitis [J]. Allergy Clin Immunol，2009， 123（6）：1349-1354.
[7] 戎露江，夏永法，钱涛，等.富含血小板血浆联合骨髓间充质干细胞治疗骨性关节炎的WOMAC评分分析[J].浙江创伤外科，2017，22（2）：294-295.
[8] Lv H，Chen W，Yuwen P，et al. Multivariate analysis of factors related to radiographic knee osteoarthritis based on the comparison between football players and matched nonsportsmen [J]. Int Orthop，2018，42（4）：1-9.
[9] Kaloria N，Bihani P，Bhatia P，et al. A Comparison of Regional Versus General Anesthesia for Lumbar Spine Surgery：An Untouched Aspect of the Meta-Analysis [J]. J Neurosurg Anesthesiol，2018，30（2）：191.
[10] 韩大鹏，成小燕，欧阳桂林.髌骨软化症中西医治疗进展[J].长春中医药大学学报，2017，33（3）：487-489.
[11] 张建光，陈路，蔚芃，等.膝骨关节炎严重程度与脊柱-骨盆矢状面平衡的相关性[J].四川医学，2017，38（5）：517-520.
[12] 孙振新，杨矛，朱玲玲，等.中医药治疗膝骨关节炎研究进展[J].辽宁中医药大学学报，2017，19（1）：111-114.
[13] Leslie WD，Shevroja E，Johansson H，et al. Risk-equivalent T-score adjustment for using lumbar spine trabecular bone score（TBS）：the Manitoba BMD registry [J]. Osteoporosis Int，2018，29（6）：1-8.
[14] Hansen BB，Hansen P，Christensen AF，et al. Reliability of standing weight-bearing（0.25T）MR imaging findings and positional changes in the lumbar spine [J]. Skeletal Radiol，2018，47（1）：25-35.
[15] Weston EB，Khan SN，Marras WS. Wheelchair pushing and turning：lumbar spine and shoulder loads and recommended limits [J]. Ergonomics，2017，60（12）：1-36.
[16] 粟迎春，雷小俊.关节腔内注射透明质酸钠联合塞来昔布治疗早中期膝关节骨关节炎的疗效分析[J].中华关节外科杂志：电子版，2017，11（2）：89-93.
[17] Choi YH，Kwon SW，Moon JH，et al. Lateral Lumbar Interbody Fusion andin SituScrew Fixation for Rostral Adjacent Segment Stenosis of the Lumbar Spine [J]. J Korean Neurosurg Soc，2017，60（6）：755-762.
[18] 刘一秀，阿良，刘哲.关节腔清理术联合透明质酸钠关节腔内注射治疗早中期膝骨关节炎的疗效分析[J].中国医科大学学报，2017，46（2）：179-181.
[19] 李勇超.循环肿瘤细胞通过诱导系统性炎症及调控中性粒细胞的功能促进播散肿瘤细胞转移克隆的形成[D].武汉：华中科技大学，2017.
[20] 黄杰华，康明，张彦，等.膝关节骨关节炎镜下清理术后联合应用得宝松、利多卡因及玻璃酸钠的疗效分析[J].中国医药科学，2017，7（14）：15-17，48.
[21] Boyadjian H，Idowu O，Mosenthal W，et al. Comparing Bleeding vs Clotting Complications after Lumbar Spine Surgery [J]. Spine J，2017，17（10）：S100. |
|
|
|
