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| The thought of treatment based on syndrome differentiation and the prescription analysis of amenorrhea treatment in Nü Ke Zhi Yao |
| JIANG Bei1 YAN Qi1 CUI Hongtao2 WANG Lichao3 DUAN Fujin1 |
1.Basic Medical College, Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150040, China;
2.Basic Medical College, Changchun University of Chinese Medicine, Jilin Province, Changchun 130117, China;
3.Center for Preventive Treatment of Disease, the First Affiliated Hospital of Changchun University of Chinese Medicine, Jilin Province, Changchun 130000, China |
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Abstract Objective Through analyzing the discussion of amenorrhea in Nü Ke Zhi Yao and its recorded prescription, to explore the dialectical way of treating amenorrhea and the law of its medication. Methods Through the study of the pulse method, treatment method, medication and prescription selection of amenorrhea article in Nü Ke Zhi Yao, the thoughts of diagnosis and treatment of Xu Dachun in the treatment of amenorrhea were mastered overall. The amenorrhea prescription was prepared to establish database, which was input into the software of traditional Chinese medicine inheritance auxiliary platform. By using the data mining method, the frequency statistics, medication mode and prescription rule of prescription were analyzed, so as to summarize the characteristics of treating amenorrhea. The selection and application of Xu Dachun for the prescription dosage form was sorted out, so as to explore the advantages of dosage form selection for amenorrhea therapy. Results Thirty-two kinds of pulse were concluded. In the prescription part, a total of 32 prescriptions were selected, involving 74 Chinese medicinal flavors. The top 10 drug frequencies were Radix Angelicae Sinensis, Radix et Rhizoma Rhei, Radix Paeoniae Alba, Semen Persicae, Cortex Cinnamomi, Rhizoma Ligustici Chuanxiong, Radix Achyranthis Bidentatae, Rhizoma Curcumae, Radix Rehmanniae Preparata and prepared Radix Glycyrrhizae. The results showed that the highest frequency of drug occurrence was the drugs of promoting blood circulation for removing blood stasis, with concerted application of nourishing blood drugs, invigorating vital energy drugs, activating qi flowing drugs and other drugs. There were 9 common drug combinations, the most frequent drug combinations were Radix Angelicae Sinensis - Radix Paeoniae Alba, Radix Angelicae Sinensis - Cortex Cinnamomi, Rhizoma Ligustici Chuanxiong - Radix Angelicae Sinensis, Radix Angelicae Sinensis - Radix et Rhizoma Rhei. The dosage forms of amenorrhea prescription were summed up, the decoction methods and characteristics of liquor application were summarized. Conclusion Xu Dachun treats amenorrhea classification carefully and pays attention to pulse diagnosis. He pays great attention to the application of promoting blood circulation for removing blood stasis drugs, he is especially good at the application of Radix et Rhizoma Rhei. And on the basis of syndrome differentiation, he adds the drugs of benefiting qi and nourishing blood, regulating vital energy and activating qi flowing, taking unobstructed as the main purpose, with reinforcement and elimination in combination. In dosage form selection of amenorrhea prescription, he uses multiple dosage forms simultaneously, pays attention to the application of pills and powders, And the decoction methods are various, which is helpful to strengthen drug potential, or protect positive qi, so that the attack against evil does not damage the positive qi.
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