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| The therapeutic effect of peribulbar injection in the treatment of diabetic ophthalmoplegia with multi-channel combined administration |
| LIU Ziyao YAO Liang HU Jia SUN Chao LIAO Dingying WANG Jianming ZHENG Yuping |
| Department of Ophthalmology, the Second Affiliated Hospital of Xi′an Jiaotong University, Shaanxi Province, Xi′an 710004, China |
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Abstract Objective To compare and analyze the effect of peribulbar injection in the treatment of diabetic ophthalmoplegia with multi-channel combined administration. Methods Sixty-eight patients with diabetic ophthalmoplegia diagnosed at the Second Affiliated Hospital of Xi'an Jiaotong University from June 2010 to April 2016 were divided into two groups according to the order of admission. Patients admitted from June 2010 to May 2013 were classified into the peribulbar injection treatment group (group A) (n = 34); patients admitted from June 2013 to April 2016 were classified into routine treatment group (group B) (n = 34). The clinical efficacy of the two groups was statistically analyzed by SPSS software. The effects of two treatment methods on the recovery of degree of eye deviation, palpebral fissure height, diplopia and eye movement were compared. Results There were no significant differences in sex, age, duration of diabetes, ratio of glycated hemoglobin and morbidity time between the two groups (P ＞ 0.05). The total effective rate of group A was significantly higher than that of group B after 1 week and 2 weeks of treatment (P ＜ 0.05), while there was no significant difference in the total effective rate between the two groups at the end of the study (3 months of treatment) (P ＞ 0.05). Conclusion Vitamin B12 and Dexamethasone injection can shorten the course of disease and accelerate the recovery of eye muscle function. However, in terms of long-term curative effect, whether it is combined with peribulbar injection or not has no significant influence on the curative effect.
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