中国中西部城市医院急性心肌梗死住院患者2001、2006、2011年β受体阻滞剂早期使用变化趋势

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Abstract Objective To assess trends of early beta-blocker use during hospitalization for ideal patients with acute myocardial infarction (AMI) and to analyze factors associated with not being treated in Central-Western Urban China from 2001 to 2011. Methods Two-stage random sampling design was used to create a representative sample of patients in Central-Western Urban China admitted to hospital for AMI. In the first phase, a simple random-sampling procedure was used to identify participating hospitals. In the second stage, a systematic sampling approach was applied for selecting patients admitted to each participating hospitals for AMI in 3 years (2001, 2006 and 2011). Then clinical information was obtained via central medical record abstraction for each patients. Weight calculation was used for each year to represent the overall situation. Logistic regression model was used to identify factors associated with early beta-blocker use. Results Finally 705 ideal candidates were included in study. Beta-blocker was used 55.5% in 2001, 74.6% in 2006, and 62.6% in 2011 (P=0.5927 for trend). Chest discomfort (OR=2.22，95% CI: 1.21-4.08) was found as the predictor of non-treatment. Conclusion The use of early beta-blocker therapy in Central-Western Urban China is suboptimal for ideal AMI patients who could definitely benefit from it. Patterns of use have not changed over time. It is urgent to implement strategy to improve clinician guidance adherence and quality of care for AMI.

Key words： Beta-blocker therapy Acute myocardial infarction Trends

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	ZHANG Lihua ZHANG Haibo BAI Xueke HUO Xiqian LIU Jiamin JIANG Lixin

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ZHANG Lihua ZHANG Haibo BAI Xueke HUO Xiqian LIU Jiamin JIANG Lixin. Early beta-blocker use in acute myocardial infarction in Central-Western Urban China in 2001, 2006, 2011[J]. 中国医药导报, 2017, 14(33): 69-73.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2017/V14/I33/69

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