脾胃老十针治疗慢性萎缩性胃炎伴肠上皮化生的临床效果

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Abstract Objective To explore the effect of “experienced ten needles for spleen and stomach” for chronic atrophic gastritis (CAG) with intestinal metaplasia (IM). Methods Fifty patients with CAG with IM treated in the Department of Spleen and Stomach, Xinjiang Autonomous Region Hospital of Traditional Chinese Medicine from March 2016 to February 2018 were selected and they were randomly divided into treatment group and control group by random number table method, with 25 cases in each group. The control group was treated with Vitacoenzyme Tablets, 1.0 g per time, tid; Domperidone Tablets, 20 mg per time, tid; and Rabeprazole Sodium Enteric-coated Capsules, 20 mg per time, qd. The course was 8 weeks. Based on the treatment above, “experienced ten needles for spleen and stomach” was given to the treatment group, the acupuncture formula: both Tianshu, both Neiguan, both Zusanli, Shangwan, Zhongwan, Xiawan, Qihai. Treating for 20 minutes per time, 5 times a week and the treatment was continuous for 8 weeks. Gastroscopy、pathological biopsy of gastric mucosa and clinical efficacy were compared before and after treatment. Results After treatment, atrophy of gastric mucosa glands improved in the two groups than that before treatment significantly (P ＜ 0.01 or P ＜ 0.05), and the improvement in the treatment group was more remarkably than the control group (P ＜ 0.05). After treatment, the improvement of intestinal metaplasia in stomach mucosa in the two groups were significant (P ＜ 0.01), and the degree of improvement in the treatment group was greater than the control group (P ＜ 0.05). After treatment, TCM symptom scores (stomach pain, stomach distension, belching and acid regurgitation, noise in the stomach, eating less, stomach oppression in the stomach after meal) decreased than those before treatment in the two groups (P ＜ 0.01 or P ＜ 0.05), and the improvement of any symptom score was more significantly in the treatment group than that in the control group (P ＜ 0.01 or P ＜ 0.05). The clinical effective rate in the intervention group was 92%, which was higher than 64% in the control group (P ＜ 0.05). Conclusion The “experienced ten needles for spleen and stomach” has a definite clinical effect for CAG with IM, which is worthy of clinical application and promotion.

Key words： “experienced ten needles for spleen and stomach” Chronic atrophic gastritis Intestinal metaplasia Effect

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	WANG Huiqing1 XU Keke2 DAI Ming2

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WANG Huiqing1 XU Keke2 DAI Ming2. Effect of “experienced ten needles for spleen and stomach” for chronic atrophic gastritis with intestinal metaplasia[J]. 中国医药导报, 2018, 15(33): 106-109.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I33/106

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