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| Clinical study of moxibustion on abdominal acupoints in the treatment of chronic kidney disease combined with functional constipation |
| MA Weizhong SU Zhuowei QU Zhanhang |
| Department of Nephrology, the Second AffIliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Province, Guangzhou 510120, China |
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Abstract Objective To explore the clinical effects of moxibustion on abdominal acupoints in the treatment of chronic kidney disease combined with functional constipation. Methods From January 2015 to February 2016, a total of 50 patients with chronic kidney disease combined with functional constipation diagnosed in Guangdong Province Traditional Chinese Medical Hospital were divided into the observation group and the control group by random number table, with 25 cases in each group. The control group was given routine treatment with mosapride citrate tablets by oral treatment and the observation group was given abdominal acupoints with moxibustion on the basis of the control group. After treatment for 1 month, the main clinical symptoms of the two groups were evaluated by the constipation symptom and efficacy evaluation questionnaire. The indexes of electrogastrography and the levels of gastrointestinal hormones were compared between the two groups. Resuts Before treatment, there were no statistically significant differences in the scores of defecation difficulty, stool character, defecation time, abnormal feeling, defecation frequency and bloating between the two groups (P ＞ 0.05). After treatment, the scores of the symptoms above in the two groups were all lower than those of before treatment, and those above in the observation group were all lower than those of control group, with statistically significant differences (all P ＜ 0.05). Before treatment, there were no statistically significant differences in the ascending colon amplitude and frequency and transverse colon amplitude and frequency between the two groups (P ＞ 0.05). After treatment, the indexes above were all higher than those of control group, and those in the observation group were much higher than those of control group, with statistically significant differences (all P ＜ 0.05). Before treatment, there were no statistically significant differences in the serum MTL, NO and SP levels (all P ＞ 0.05). After treatment, the MTL and SP were much higher than those of before treatment, the NO was much lower than that of before treatment, and those indexes above changed much more significant, with statistically significant differences (all P ＜ 0.05). Conclusion The clinical effects of moxibustion on abdominal acupoints in the treatment of chronic kidney disease combined with functional constipation is good, can regulate the patients′ gastrointestinal hormone disorder, improve the gastrointestinal function, relieve the constipation symptoms.
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