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| A study on the diagnostic value of intranperative fast frozen sections in disease severity of patients with endometrial cancer |
| ZHOU Chanping1 ZHANG Pu1 CHEN Wanwan1 ZHOU Lingli1 LI Xiangyang2 |
1.Department of Pathology, the Second Affiliated Hospital, Wenzhou Medical University, Zhejiang Province, Wenzhou 325000, China;
2.Clinical Laboratory, the Second Affiliated Hospital, Wenzhou Medical University, Zhejiang Province, Wenzhou 325000, China |
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Abstract Objective To explore the diagnostic value of intranperative fast frozen sections in disease severity of patients with endometrial cancer, in order to provide reference for the clinical diagnosis and treatment of endometrial carcinoma. Methods Form January 2010 to December 2016, 80 patients with endometrial cancer in the Second Affiliated Hospital of Wenzhou Medical University were selected. They were treated by normal endometrial carcinoma stage operation, histopathological examination of fast frozen sections in intraoperative procedure, routine pathological examination after surgery (gold standard). The sensitivity and specificity for fast frozen sections diagnosis of endometrial carcinoma were analyzed. Results The diagnostic results showed that fast frozen sections in the operation and postoperative pathological examination were endometrial carcinoma. The sensitiveness and specificity of low differentiated were higher than that of high differentiated and moderately differentiated (P < 0.05). The sensitiveness for type Ⅰ was higher than type Ⅱ, the specificity for type Ⅰ was lower than type Ⅱ (P < 0.05). The sensitiveness for deep muscular layer infiltration was higher than shallow muscular layer infiltrates, the specificity for deep muscular layer infiltration was lower shallow muscular layer infiltrates (P < 0.05). Conclusion It has diagnostic value for the patients with endometrial cancer by fast frozen sections in the operation, while it has some differences in the results of postoperative pathological examination.
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