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| The value of NT-proBNP and P wave dispersion in the diagnosis and prognosis of patients with paroxysmal atrial fibrillation |
| YAN Chao1 WANG Ling2 |
1.The First Department of Internal Medicine, Inner Mongolia Fourth Hospital, Inner Mongolia Autonomous Region, Huhhot 010000, China;
2.Department of Cardiology, Inner Mongolia People′s Hospital, Inner Mongolia Autonomous Region, Hohhot 010017, China |
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Abstract Objective To analyse the changes of N-terminal pro-brain natriuretic peptide (NT-proBNP) level and P wave dispersion (Pd) in patients with paroxysmal atrial fibrillation (PAF), and provide the reference for the diagnosis and prognosis of PAF. Methods One hundred and thirty PAF patients in Inner Mogolia People′s Hospital were selected as the atrial fibrillation group and 50 healthy physical examination people were selected as control group. The changes of NT-proBNP level and Pd value of the two groups before and after cardioversion were analyzed, patients in the atrial fibrillation group were followed up for 6 months after discharge. The relationship between the NT-proBNP level and the Pd value before and after the cardioversion of atrial fibrillation was analyzed. Results The level of NT-proBNP before cardioversion in the atrial fibrillation group was significantly higher than that in the control group (P < 0.05); the level of NT-proBNP after cardioversion in the atrial fibrillation group was lower than that before cardioversion, which was still higher than that in the control group, the differences were statistically significant (P < 0.05). The Pd value before cardioversion in the atrial fibrillation group was significantly higher than that in the control group (P < 0.05); the Pd value after cardioversion in the atrial fibrillation group was lower than that before cardioversion (P < 0.05), but it had no significant difference compared with that in the control group (P > 0.05). After diacharge for 3 months, the level of NT-proBNP before cardioversion in the recurrent PAF group was higher than that in the non recurrent PAF group before cure, the difference was statistically significant (P < 0.05). After discharge for 3, 4, 5, 6 months, the level of NT-proBNP after cardioversion in the recurrent PAF group was higher than that in the non recurrent PAF group after cardioversion, the differences were statistically significant (P < 0.05). Conclusion The NT-proBNP level and Pd value have good application value for the diagnosis and prognosis of patients with PAF.
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