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| Effect of hyaluronic acid on maternal inflammatory factors and intrauterine adhesions after cesarean section |
| LIU Jieling LIANG Yuan |
| Department of Gynaecology and Obstetrics, Haikou Third People′s Hospital, Hainan Province, Haikou 571100, China |
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Abstract Objective To analyze the effect of hyaluronic acid on maternal inflammatory factors and intrauterine adhesions after obstetric cesarean section. Methods A total of 90 pregnant women with cesarean section form May 2016 to May 2017 in Department of Gynaecology and Obstetrics of Haikou Third People′s Hospital were selected and divided into the control group and observation group by random number table method, with 45 cases in each group. Pregnant women in observation group were given the treatment of medical hyaluronic acid after cesarean section, while the control group without any therapy after cesarean section. The incidences of intrauterine adhesion, inflammatory factor levels and pain degree were compared between the two groups. Results The total incidence of postpartum adhesion in observation group was lower than control group, and the difference was significant (P < 0.05). The levels of serum IL-6, IL-10 and pain degree of two groups 3 d after treatment were all higher than those before treatment, the levels of the above indexes, were significantly reduced 7 d after treatment, while those were still higher than those before treatment, and the differences were significant (P < 0.05). The L-6, IL-10, TNF-α and pain degree of the observation group 3 and 7 d after treatment were obviously lower than those of the control group, and the differences were significant (P < 0.05). Conclusion The application of hyaluronic acid can effectively prevent adhesion, improve postoperative inflammatory factors, and relieve pain for pregnant women after cesarean, it is worthy of clinical application.
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