丽水市胃癌危险因素的病例对照研究

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Abstract Objective To investigate the risk factors of gastric cancer in Lishui City. Methods Two hundred and ten cases of gastric cancer diagnosed by pathology, that were treated in hospitals above the country level in Lishui City were enrolled in this study as case group from March 2012 to February 2015. The method, 1∶1 matched case-control study was used, 2010 healthy people in each country and districts in Lishui City were randomly selected as the control group. By means of “Questionnaire of the Survey of Living and Health of the Population”, the correlation factors of gastric cancer patients and control population were investigated and the relationship between these factors and gastric cancer was analyzed. Results Through the one-way ANOVA, it showed that frequent drinking, frequent green tea drinking, impatience, history of stomach disease, eating fast, often eating midnight snacks, often eating out, often eating salted foods, often eating fresh vegetables were found to be statistically different between the case group and the control group (P ＜ 0.05). After controlling and considering other confounding factors, via multiple Logistic analysis method often eating salted food (OR = 19.662, 95%CI:10.000-38.658, P = 0.000), often eating midnight snacks (OR = 2.494, 95%CI:1.297-4.807, P = 0.006), eating fast (OR = 4.329, 95%CI:2.273-8.264, P = 0.000), the history of stomach problems (OR = 2.033, 95%CI:1.004-4.119, P = 0.049) were found to be major risk factors of gastric cancer in Lishui; often drinking green tea (OR = 0.330, 95%CI:0.169-0.647, P = 0.001), often eating fresh vegetables (OR = 0.439, 95%CI:0.213-0.907, P = 0.026) were found to be protective factors. Conclusion The incidence of gastric cancer in Lishui City is closely related to eating habits. Changing unhealthy eating habits is an important way to reduce the incidence of gastric cancer in this area.

Key words： Gastric cancer Risk factors Case control study Eating habits

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	ZHOU Yuefen WU Minhua XIE Yanru LIU Wujing WANG Yonghui LOU Jian

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ZHOU Yuefen WU Minhua XIE Yanru LIU Wujing WANG Yonghui LOU Jian. A case control study of gastric cancer risk factors in Lishui City[J]. 中国医药导报, 2018, 15(24): 45-50.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I24/45

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