玻璃纤维桩联合BisCem树脂水门汀对残根残冠修复患者PGE2、IL-1β水平的影响

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Abstract Objective To investigate the effect of glass-fiber post combined with BisCem resin cement on levels of prostaglandin E2 (PGE2) and interleukin-1β (IL-1β) of gingival crevicular fluid in patients with restoration of residue crown and residue root. Methods From October 2015 to June 2017, 84 patients with restoration of residue crown and residue root in Department of Stomatology of Nanjing Mingji Hospital were randomly divided into control group (n = 42) and study group (n = 42). The two groups were all repaired with glass-fiber post and resin material. The study group was treated with BisCem resin cement and the control group was treated with PULPDENT dual-curing resin cement. The masticatory efficacy(bite force, chewing efficiency) before treatment and after 1 month of treatment, the level of PGE2 and IL-1β in gingival crevicular fluid before treatment and after 3 d and 5 d of treatment, the satisfaction and the incidence of complications were statistically analyzed between the two groups. Results There was insignificant difference in masticatory efficiency and bite force between the two groups before treatment(P ＞ 0.05). After 1 month of treatment, the masticatory efficiency and bite force of the two groups increased compared with those before treatment, and the study group was larger than the control group(P ＜ 0.05). There was insignificant difference in levels of PGE2 and IL-1β of gingival crevicular fluid between the two groups before treatment (P ＞ 0.05). After treatment, the levels of PGE2 and IL-1β of gingival crevicular fluid of the two groups increased, but those in the study group were lower than those in the control group(P ＜ 0.05). The repair effect, comfort degree, masticatory ability and the satisfaction score of appearance effect of the study group were higher than those of the control group(P ＜ 0.05). The total incidence of complications in the study group (9.52%) was lower than that in the control group (26.19%) (P ＜ 0.05). Conclusion Glass-fiber post combined with BisCem resin cement in treating patients with restoration of residue crown and residue root is beneficial to improve the masticatory efficacy, reduce the degree of trauma, and inhibit the increase of PGE2 and IL-1β levels of gingival crevicular fluid, and improve the satisfaction of the treatment. Besides, the incidence of complications is lower and the safety is higher.

Key words： Glass-fiber post BisCem resin cement Restoration of residue crown and residue root Masticatory efficiency Prostaglandin E2 Interleukin-1β

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WU Yuanyuan. Effect of glass-fiber post combined with BisCem resin cement on levels of PGE2 and IL-1β in patients with restoration of residue crown and residue root[J]. 中国医药导报, 2018, 15(21): 102-105.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I21/102

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