旋极针法对含铂化疗方案治疗恶性肿瘤减毒作用的临床研究

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Abstract Objective To study the clinical effect of Xuanji acupuncture method on attenuation effects of Platinum chemotherapy regimen in the treatment of malignant tumor. Methods Fifty-nine patients with malignant tumor treated in Guangdong Provincial Hospital of Traditional Chinese Medicine from July to December 2017 were selected and randomly divided into observation group (29 cases) and control group (30 cases) according to the random number table method. Both groups were treated with Platinum chemotherapy regimen routinely for 2 courses, while the observation group was treated with Xuanji acupuncture during chemotherapy for 10 days. The cellular immune function, quality of life, bone marrow suppression conditions and digestive tract reactions before and after treatment between the two groups were compared. Results After treatment, the levels of CD3+, CD4+, CD8+ and CD4+/CD8+ in the observation group were significantly higher than those before treatment; the levels of CD3+ and CD4+ in the control group were significantly higher than those before treatment (all P ＜ 0.05). After treatment, the levels of CD3+, CD4+, CD8+ and CD4+/CD8+ in the observation group were significantly higher than those of the control group (P ＜ 0.05). In European organization for research and treatment of cancer (EORTC) QLQ-C30, the score of total health in the observation group was significantly higher than that of the control group, while the scores of nausea, vomiting, pain and appetite were significantly lower than those of the control group (all P ＜ 0.05). The incidence of bone marrow suppression and digestive tract reaction in the observation group were significantly lower than those in the control group (all P ＜ 0.05). Conclusion Xuanji acupuncture method combined with Platinum chemotherapy regimen can reduce toxicity function of patients with malignant tumor, and it can improve the immune function and quality of life, which may deserve for clinical promotion.

Key words： Xuanji acupuncture method Platinum chemotherapy regimen Malignant tumor Attenuation effects

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	Articles by authors
	LIAO Guiya1
	2 LONG Shunqin1
	2 DENG Hong1
	2 LI Qiuping1
	2 HUANG Jinpeng1
	2 GAN Ziyan1
	2 BI Jiayi1
	2 LIU Yu1

Cite this article:

LIAO Guiya1,2 LONG Shunqin1,2 DENG Hong1, et al. Clinical study of Xuanji acupuncture method on attenuation effects of Platinum chemotherapy regimen in the treatment of malignant tumor[J]. 中国医药导报, 2018, 15(19): 117-120.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I19/117

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