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| Effects of Shuxuetong Injection on serum inflammatory factors and platelet activating factors in patients with acute cerebral infarction |
| LI Xiang1 CAO Yan2 QU Lei3 |
1.Emergency Department, Beijing Shijingshan Hospital, Beijing 100043, China;
2.Department of Internal Medicine-Neurology, Beijing Shijingshan Hospital, Beijing 100043, China;
3.Medical Department, Beijing Shijingshan Hospital, Beijing 100043, China |
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Abstract Objective To study the effects of Shuxuetong Injection on serum inflammatory factors and platelet activating factors in patients with acute cerebral infarction (ACI). Methods Sixty patients with ACI admitted to Beijing Shijingshan Hospital from April 2015 to December 2016 were randomly divided into the conventional treatment group and the study group, with 30 cases in each group. The conventional treatment group was treated with the conventional western medicine, on basis of which, the study group was treated with Shuxuetong Injection. The clinical effects of the two groups were compared. The national institute of health neurological impairment scale (NIHSS) and Barthel index (BI) were evaluated. The serum inflammatory factors and platelet activating factors were examined before and after treatment. Results The total efficacy rate of the study group was 93.33%, which was significantly higher than 73.33% of the conventional treatment group (P ＜ 0.05). After treatment, the NIHSS scores of the two groups were significantly reduced, BI scores were significantly increased, and the improvement of NIHSS, BI in the study group was significantly better than that of conventional treatment group, the differences were all statistically significant (all P ＜ 0.05). After treatment, the levels of serum inflammatory factors and platelet activating factors in the two groups were all significantly decreased, and the levels of serum inflammatory factors and platelet activating factors in the study group were significantly lower than those in the conventional treatment group, the differences were all statistically significant (all P ＜ 0.05). Conclusion Shuxuetong Injection for patients with acute cerebral infarction has a good efficacy, which can improve the nervous function and daily life, reduce the serum inflammatory factors and platelet activating factors, and it is worthy of clinical promotion and application.
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