冥想干预对残留型精神分裂症患者认知功能的疗效

Abstract
Figure/Table
References (25)
Related Citation (15)

Download: PDF (573 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To explore the curative effect of meditation intervention on cognitive function in patients with residual schizophrenia. Methods From January to April 2019, sixty patients with residual schizophrenia were recruited from Shanghai No.1 Civil Administration Mental Health Center who had been hospitalized in for a long time. The patients were divided into control group and meditation group by random number table method. The control group (n = 30) received conventional treatment, and the meditation group (n = 30) received meditation intervention for 8 months in addition to conventional treatment. Cognitive function and psychotic symptoms were assessed before admission and at the end of 8 months after treatment with the repeatability battery for the assessment of neuropsychological status (RBANS) and the brief psychiatric rating scale (BPRS) assesses psychotic symptoms. Results After intervention, the total scores of immediate memory and RBANS in the meditation group were higher than those before intervention, and the total scores of immediate memory, visual span, speech function and attention in the meditation group were higher than those in the control group, with statistical significances (P ＜ 0.05). After intervention, the total score of BPRS scale, anxiety and depression, inactivity, activation and hostile suspicion in the meditation group were lower than those before intervention, and the total score of BPRS scale, anxiety and depression, inactivity and activation scores in the meditation group were lower than those in the control group, the differences were statistically significant (P ＜ 0.05). Conclusion Meditation intervention on the basis of conventional treatment for patients with residual schizophrenia can improve cognitive impairment and psychotic symptoms, and promote rehabilitation.

Key words： Meditation intervention Residual schizophrenia Cognitive function Cohort follow-up

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	GU Yan1 GAO Hongrui1 YANG Xianghong1 DAI Jingjing1 YAN Zhen1 ZHANG Chen2▲

Cite this article:

GU Yan1 GAO Hongrui1 YANG Xianghong1 DAI Jingjing1 YAN Zhen1 ZHANG Chen2▲. Curative effects of meditation intervention on cognitive function in patients with residual schizophrenia[J]. 中国医药导报, 2021, 18(7): 91-94.

URL:

http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2021/V18/I7/91

[1] 陆如平，高慧，彭红，等.改良道家认知疗法对男性残留型精神分裂症患者阴性症状及认知功能改善作用的研究[J].精神医学发志，2019，32（2）：86-91.
[2] Taylor J，McLean L，Korner A，et al. Mindfulness and yoga for psychological trauma：systematic review and meta-analysis [J]. J Trauma Dissociation，2020，26：1-38.
[3] Kang H，An SC，Kim NO，et al. Meditative Movement Affects Working Memory Related to Neural Activity in Adolescents：A Randomized Controlled Trial [J]. Front Psychol，2020，11：931.
[4] Rodriguez-Larios J，Faber P，Achermann P，et al. From thoughtless awareness to effortful cognition：alpha- theta cross-frequency dynamics in experienced meditators during meditation，rest and arithmetic [J]. Sci Rep，2020，10（1）：5419.
[5] World Health Organization. The ICD-10 classification of mental and behavioural disorders：clinical description and diagnostic guidelines [J]. Geneva：World Health Organization，1992.
[6] Huberty J，Green J，Glissmann C，et al. Efficacy of the Mindfulness Meditation Mobile App “Calm” to Reduce Stress Among College Students：Randomized Controlled Trial [J]. JMIR Mhealth Uhealth，2019，7（6）：e14273
[7] Lebares CC，Guvva EV，Olaru M，et al. Efficacy of Mindfulness-Based Cognitive Training in Surgery：Additional Analysis of the Mindful Surgeon Pilot Randomized Clinical Trial [J]. JAMA Netw Open，2019，2（5）：e194108.
[8] Pressman A，Law H，Stahl R，et al. Conducting a pilot randomized controlled trial of community-based mindfulness-based stress reduction versus usual care for moderate-to-severe migraine：protocol for the Mindfulness and Migraine Study （M&M） [J]. Trials，2019，20（1）：257.
[9] Zhang Y，Fang X，Fan W，et al. Interaction between BDNF and TNF-α genes in schizophrenia [J]. Psychoneuroendocrinology，2018，89：1-6.
[10] Fang X，Chen Y，Wang Y，et al. Depressive symptoms in schizophrenia patients：A possible relationship between SIRT1 and BDNF [J]. Prog Neuropsychopharmacol Biol Psychiatry，2019，95：109673.
[11] Fang X，Chen Y，Wang Y，et al. Identification of risk factors for suicidal ideation in patients with schizophrenia [J]. Psychiatry Res，2019，271：195-199.
[12] Womer FY，Tang Y，Harms MP，Bai C，et al. Sexual dimorphism of the cerebellar vermis in schizophrenia [J]. Schizophr Res，2016，176（2/3）：164-170.
[13] Ayd?覦n MS，Bolu A，K?覦l?覦n?觭kaya MF，et al. Brain-derived neurotrophic factor levels and psychopathology scores in drug-na?觙ve first-episode psychosis [J]. Asia Pac Psychiatry，2020：e12415.
[14] Wang J，Zhang Y，Liu Z，et al. Schizophrenia patients with a metabolically abnormal obese phenotype have milder negative symptoms [J]. BMC Psychiatry，2020，20（1）：410.
[15] Grigoriou M，Upthegrove R. Blunted affect and suicide in schizophrenia：A systematic review [J]. Psychiatry Res，2020，293：113355.
[16] Hallett M，de Haan W，Deco G，et al. Human brain connectivity：Clinical applications for clinical neurophysiology [J]. Clin Neurophysiol，2020，131（7）：1621-1651.
[17] Areal LB，Blakely RD. Neurobehavioral changes arising from early life dopamine signaling perturbations [J]. Neurochem Int，2020，137：104747.
[18] Rung AL，Oral E，Berghammer L，et al. Feasibility and Acceptability of a Mobile Mindfulness Meditation Intervention Among Women：Intervention Study [J]. JMIR Mhealth Uhealth，2020，8（6）：e15943.
[19] Amarasekera AT，Chang D. Buddhist meditation for vascular function：A narrative review [J]. Integr Med Res，2019，8（4）：252-256.
[20] Mathersul DC，Tang JS，Schulz-Heik RJ，et al. Study protocol for a non-inferiority randomised controlled trial of SKY breathing meditation versus cognitive processing therapy for PTSD among veterans[J]. BMJ Open，2019，9（4）：e027150.
[21] Ziegler DA，Simon AJ，Gallen CL，et al. Closed-loop digital meditation improves sustained attention in young adults [J]. Nat Hum Behav，2019，3（7）：746-757.
[22] Wolff N，Beste C. Short-term Smartphone App-based Focused Attention Meditation Diminishes Cognitive Flexibility [J]. J Cogn Neurosci，2020，22：1-12.
[23] Gabriely R，Tarrasch R，Velicki M，et al. The influence of mindfulness meditation on inattention and physiological markers of stress on students with learning disabilities and/or attention deficit hyperactivity disorder [J]. Res Dev Disabil，2020，100：103630.
[24] Tang YY，Fan Y，Lu Q，et al. Long-Term Physical Exercise and Mindfulness Practice in an Aging Population [J]. Front Psychol，2020，11：358.
[25] Love MF，Sharrief A，LoBiondo-Wood G，et al. The Effects of Meditation，Race，and Anxiety on Stroke Survivor Resilience [J]. J Neurosci Nurs，2020，52（3）：96-102.