体外冲击波治疗膝骨性关节炎的meta分析

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Abstract Objective To systematically assess the clinical effect of extracorporeal shock wave therapy （ESWT） for knee osteoarthritis (KOA). Methods From the establishment of the database to February 20, 2019, the databases of PubMed, Embase, Web of Science, the Cochrane Library, CNKI, CBM, VIP, WanFang were searched, and the clinical randomized controlled trials of ESWT in the treatment of KOA were searched. According to inclusion and exclusion criteria, the literature were screened with 2 researchers, the data and the quality of the included literature were extracted and evaluated. RevMan 5.3 was used for data analysis. Results A total of 11 articles, 969 cases were included. The results of meta analysis showed that, VAS scores in ESWT group were lower than those in control group, with statistically significant differences (MD = -2.07, 95%CI: -3.83, -0.31, P < 0.05). Western Ontario and Mcmaster University Osteoarthritis index (WOMAC) in ESWT group were significantly lower than those in control group, with statistically significant differences (MD = -9.06, 95%CI: -14.36, -3.76, P < 0.01). There was no significant difference in shedding rate between the two groups (OR = 0.82, 95%CI: 0.28, 2.45, P > 0.05). The results of the subgroup analysis showed that the VAS scores in ESWT group were significantly lower than those in drug group, with statistically significant differences (MD = -1.99, 95%CI: -3.58, -0.41, P < 0.05). VAS scores in ESWT group were significantly lower than those in ultrasonic group, with statistically significant differences (MD = -1.11, 95%CI: -1.98, -0.23, P < 0.05). VAS scores in ESWT group and sodium hyaluronate group showed no significant differences (MD = -2.86, 95%CI: -9.23, -3.51, P > 0.05). Conclution ESWT improves pain, stiffness, and somatic function in the short term.

Key words： Extracorporeal shock wave therapy Knee osteoarthritis Meta analysis

About author:: 余绍涌（1994.11-），男，广西中医药大学研究生院2017级中医骨伤专业在读硕士研究生；研究方向：中医骨伤科学。

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	YU Shaoyong1 LIU Jianhang2 ZHOU Hanjing1 WU Haibo1 XIE Guixin1 LI Jinwei3

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YU Shaoyong1 LIU Jianhang2 ZHOU Hanjing1 WU Haibo1 XIE Guixin1 LI Jinwei3. Meta analysis of extracorporeal shock wave therapy in the treatment of knee osteoarthritis[J]. 中国医药导报, 2020, 17(3): 69-73.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2020/V17/I3/69

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