中医药治疗消化性溃疡的Meta分析再评价

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Abstract Objective To comprehensively summarize the meta-analysis on peptic ulcer treated with traditional Chinese medicine (TCM), and to evaluate the methodological quality of meta-analysis and evidence quality of outcomes. Methods Eight databases including CNKI, Wanfang, VIP, OVID, CBM, PubMed, Embase, Cochrane Library were searched to collect the published meta-analysis on peptic ulcer treated with TCM. The time was from the inception to March 2019. Two researchers conducted literature screening and data extraction independently. The methodological quality of meta-analysis was assessed by using AMSTAR2 tool. The evidence quality was evaluated by using GRADE system. Results Finally, 11 meta-analysis were included, including 38 outcomes. The results of AMSTAR showed that 2 meta-analysis had moderate methodological quality, 3 had low quality, and 6 had very low quality. Results of GRADE showed that 21 outcomes were low quality evidence, 14 outcomes were very low quality evidence, and only 3 outcomes were moderate quality evidence. Conclusion The overall methodological quality of meta-analysis on peptic ulcer treated with TCM is low, and the evidence quality of outcome is generally low, indicating low reliable results. High quality meta-analysis should be conducted in the future for further verification.

Key words： Peptic ulcer Traditional Chinese medicine Meta-analysis Overview

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	LI Liqun1 LIU Hongwu1 GONG Xiaokun1 CHEN Guangwen2 SONG Qingzeng1 TAN Jinjing2 XIE Sheng2

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LI Liqun1 LIU Hongwu1 GONG Xiaokun1 CHEN Guangwen2 SONG Qingzeng1 TAN Jinjing2 XIE Sheng2. Revaluation of traditional Chinese medicine in the treatment of peptic ulcer by meta-analysis[J]. 中国医药导报, 2019, 16(36): 127-131.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2019/V16/I36/127

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