巨噬细胞自噬在炎症性疾病中的作用研究进展

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Abstract Macrophages are one of the important innate immune cells in the body, which are involved in immune defense and regulation of inflammation. Autophagy can regulate the phagocytosis and antigen presenting function of macrophages. It can also regulate the role of macrophages in the occurrence, development and regression of inflammation by regulating the polarization direction of macrophages. Macrophage autophagy is involved in the occurrence, development and regression of many inflammatory diseases, such as sepsis, acute lung injury, inflammatory liver injury, atherosclerosis, rheumatoid arthritis and so on. This article reviews the research progress of macrophage autophagy in inflammatory diseases, and analyzes the possibility of macrophage autophagy as a potential target for treatment of inflammatory diseases.

Key words： Macrophage Autophagy Inflammatory diseases Immunity

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	CHENG Mengqun YIN Jianbin ZHANG Xuan

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CHENG Mengqun YIN Jianbin ZHANG Xuan. Research progress on the role of macrophage autophagy in inflammatory diseases[J]. 中国医药导报, 2019, 16(21): 35-38.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2019/V16/I21/35

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