三维斑点追踪技术在2型糖尿病患者左心室功能评价中的应用效果

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Abstract Objective To investigate the application effect of three-dimensional speckle tracking technology (3D-STI) in the evaluation of left ventricular function in patients with type 2 diabetes mellitus. Methods From January 2017 to April 2018, 81 patients with type 2 diabetes mellitus from the First Affiliated Hospital of Hebei North University ("our hospital" for short) were selected. According to whether the intima-media thickness (IMT) of the common carotid artery was thickened, it was divided into TM1 group (IMT≤1.0 mm) (n = 38) and TM2 group (1.0 mm<IMT<1.2 mm) (n = 43), and healthy subjects with matched age and gender in the same period in our hospital were selected as the control group (n = 40). Left ventricular global longitudinal strain (GLS), circumferential strain (GCS), area strain (GAS), radial strain (GRS), left ventricular ejection fraction (LVEF), carotid IMT and related clinical indicators were compared in each group, and the correlation between strain values and IMT and glycated hemoglobin (HbA1c) was analyzed. Results Compared with the control group, GLS in TM1 group decreased, and the difference was statisticlly significant (P < 0.05). Compared with the control group and the TMI group, GLS, GCS, GAS and GRS in TM2 group decreased significantly (P < 0.01 or P < 0.05), IMT and HbA1c were negatively correlated with left ventricular strain in all directions (r < 0, P < 0.05). Conclusion Subclinical left ventricular dysfunction in early stage of type 2 diabetes mellitus can be detected by 3D-STI. If carotid IMT thickening occurs, left ventricular systolic function will be further impaired and left ventricular ejection fraction will be reduced. 3D-STI is a sensitive method to detect these slight abnormalities.

Key words： Three-dimensional speckle tracking technology Diabetes mellitus Left ventricular function

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	XU Le1 WEN Dehui1▲ ZHENG Yingjuan1 SHI Baolin2 LIU Weiliang1 GU Jun3

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XU Le1 WEN Dehui1▲ ZHENG Yingjuan1 SHI Baolin2 LIU Weiliang1 GU Jun3. Application effect of 3D-STI in the evaluation of left ventricular function in patients with type 2 diabetes[J]. 中国医药导报, 2019, 16(21): 177-180.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2019/V16/I21/177

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