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| Application and prospect of PDX model in ovarian cancer researches |
| LI Wei YANG Shuli TIAN Ming MIAO Jinwei▲ |
| Department of Gynecologic Oncology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100071, China |
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Abstract Ovarian cancer is a common gynecology oncologic tumor. Its clinical presentations are untypical, mainly including abdominal distension and pelvic mass, et al. The pathologic types of ovarian cancer are varied, so its heterogenicity is obvious. Tumor cell line modals and transgenic animal modals are commonly used ovarian cancer models, and they gain great progress in ovarian cancer researches. But their defects are also inevitable. Ovarian cancer patient derived tumer xenograft (PDX) model is a brand new cancer research model, we summarize the application base and prospect of it PDX model ovarian cancer researches.
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