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| Effect of integrated traditional Chinese and Western medicine on 5-year survival of children with malignant solid tumors |
| ZHANG Ji1 SHI Xue2▲ LI Haitian3 ZHU Xiudan4 TIAN Li5 LIU Zhengmao6 |
1.Department of Pediatrics, Mentougou District Hospital of Traditional Chinese Medicine in Beijing City, Beijing 102300, China;
2.Department of Traditional Chinese Medicine, National Children′s Medical Center Beijing Children′s Hospital, Capital Medical University, Beijing 100045, China; 3.Department of Rehabilitation, National Children′s Medical Center Beijing Children′s Hospital, Capital Medical University, Beijing 100045, China;
4.Department of Oncology Surgery, National Children′s Medical Center Beijing Children′s Hospital, Capital Medical University, Beijing 100045, China;
5.Department of Pediatrics, Xuanwu Hospital of Traditional Chinese Medicine in Beijing City, Beijing 100053, China; 6.Department of Pediatrics, Xiangyang Traditional Chinese Medicine Hospital, Hubei Province, Xiangyang 441000, China |
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Abstract Objective To explore the effect on 5-year survival of integrated traditional Chinese and Western medicine to children with malignant solid tumors. Methods The subjects were 167 children with malignant solid tumors admitted to Beijing Children′s Hospital, Capital Medical University from January 2005 to December 2009, continuous return visit for 5 years, up to January 2015. The children who met the inclusion criteria were divided into treatment group (83 cases) and control group (84 cases) by random number table method. Among them, there were 67 cases in treatment group (16 cases of exfoliation) and 64 cases in control group (20 cases of exfoliation). The treatment group received routine chemotherapy, surgery and traditional Chinese medicine, while the control group received routine chemotherapy and surgery. The survival time, survival and recurrence conditions of two groups were compared. Results The 5-year survival rate was 69.0% in treatment group and 46.7% in control group, there was significant difference in the average survival time between two groups (P ＜ 0.01). There was no significant difference in recurrence rate between two groups (P ＞ 0.05). There was significant difference in disease-free survival between two groups (P ＜ 0.05). Conclusion Fuzheng Jianpi traditional Chinese medicine combined with Western medicine in the treatment of children with solid tumors can successfully complete chemotherapy, prolong the survival time, improve the survival rate and improve the quality of life by reducing adverse reactions of chemotherapy.
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