脑血疏口服液对脑梗死患者血液流变学、同型半胱氨酸及血管内皮生长因子的影响

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Abstract Objective To observe the effect of Naoxueshu oral liquid on cerebral infarction and its effect on hemorheology, homocysteine and vascular endothelial growth factor (VEGF). Methods from February 2017 to February 2018, 70 cases of cerebral infarction patients admitted to Tangjiazhuang Hospital, Kailuan, Hebei Province were selected and divided into observation group and control group by random number table method, with 35 cases in each group. Patients in both groups were given symptomatic treatment such as anticoagulation, anti-platelet aggregation, dehydration, reducing intracranial pressure, and scavenging oxygen free radicals, etc, and the observation group was given cerebrohemohy Naoxueshu therapy on this basis. The therapeutic effect, NIHSS, mRS score, hemorheology, Hcy and hs-CRP were compared between the two groups. Results After treatment, the NIHSS and mRS scores of patients in the two groups were lower than those before treatment, and the differences were statistically significant (P ＜ 0.05), the NIHSS and mRS scores of the observation group were lower than those of the control group, and the differences were statistically significant (P ＜ 0.05). Hcy and hs-CRP in the two groups decreased compared with that before treatment, and the differences were statistically significant (P ＜ 0.05). Hcy, hs-CRP and VEGF levels in the observation group were lower than those in the control group, with statistically significant differences (P ＜ 0.05), fibrinogen, plasma viscosity, low whole blood viscosity, medium whole blood viscosity and high whole blood viscosity of the two groups were all lower than before treatment, and the differences were statistically significant (P ＜ 0.05), the indexes of hemorheology in the observation group were lower than those in the control group, and the differences were statistically significant (P ＜ 0.05). The total effective rate in the observation group was higher than that in the control group, and the difference was statistically significant (P ＜ 0.05). Conclusion The treatment of cerebral infarction patients with cerebral blood thinning oral liquid is helpful to improve blood coagulation function, promote nerve function repair, and improve the quality of life of patients.

Key words： Naoxueshu Cerebral infarction Life quality Neurological function

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CAO Suhong. Effects of Naoxueshu oral liquid on hemorheology homocysteine and vascular endothelial growth factor in patients with cerebral infarction[J]. 中国医药导报, 2019, 16(11): 58-61.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2019/V16/I11/58

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