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| Correlation analysis of N-terminal pro-brain natriurctic peptide and left atrial volume with recurrence after radiofrequency catheter ablation of atrial fibrillation |
| GUO Fei XU Jian SU Hao ZHU Hongjun CHEN Kangyu ZHU Jing |
| Department of Cardiology, the First Affiliated Hospital of University of Science and Technology of China Anhui Provincial Hospital, Anhui Province, Hefei 230001, China |
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Abstract Objective To investigate the correlation of N-terminal pro-brain natriurctic peptide (NT-proBNP) and left atrial volume (LAV) with the recurrence after atrial fibrillation catheter radiofrequency ablation in patients with atrial fibrillation. Methods One hundred and six patients with paroxysmal atrial fibrillation treated in First Affiliated Hospital of University of Science and Technology of China from May 2017 to January 2018 were selected as the research subjects, all patients were performed radiofrequency ablation of atrial fibrillation catheter. The plasma NT-proBNP level before operation was detected by chemiluminescent immunoassay, LAV of the patients was measured by transesophageal echocardiography. Three months was followed-up after operation, according to whether recurrence occurred, the patients were divided into recurrence group and non-recurrence group. Logistic multivariate regression analysis was used to analyze the risk factors for recurrence after radiofrequency catheter ablation of atrial fibrillation. Results Follow-up observation showed that 16 cases recurred after operation, and the recurrence rate was 14.68%. The plasma NT-proBNP and LAV of the recurrence group were higher than those of the non-recurrence group, the differences were statistically significant (P < 0.05). Multivariate Logistic regression analysis showed that plasma NT-proBNP and LAV were independent risk factors for recurrence after radiofrequency catheter ablation of paroxysmal atrial fibrillation (P < 0.05). Conclusion The levels of plasma NT-proBNP and LAV before operation in patients with recurrent atrial fibrillation after radiofrequency catheter ablation are independent risk factors for recurrence after operation, detection of plasma NT-proBNP and LAV before operation can help predict the recurrence of patients after operation.
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