肾氧饱和度监测在婴幼儿非紫绀型先心病手术中的应用及临床意义

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Abstract Objective To explore the clinical significance of continuous renal oxygen saturation monitoring. Methods Fifty cases 3 months - 3 years old children with acyanotic congenital heart disease accepted surgical treatment from January to November 2017 in Shenzhen Children Hospital were selected. Sufentanil Sevoflurane inhalation combined with tracheal intubation anesthesia were used. At the time point of before anesthesia (t0), 5 min after anesthesia (t1), 5 min after operation (t2), 5 min after cardiopulmonary bypass (t3), 15 min after cardiopulmonary bypass (t4) the beginning of CPB, after open aortic 5 min (t5), 5 min after closing the anaesthesia machine (t6) and ending of the surgery (t7), the renal regional oxygenation saturation (RrSO2), cerebral regional oxygen saturation (CrSO2), mean arterial pressure (MAP), the nose temperature and rectal temperature and other changes were recorded. Results At the time point of t3, t4, t5, t6, t7, RrSO2 and CrSO2 were higher than t0, the differences were statistically significant (P < 0.05). RrSO2 was positively correlated with CrSO2 (r = 0.682, P = 0.000), and RrSO2 was positively correlated with MAP (r = 0.258, P = 0.061), and negatively correlated with nose temperature, rectal temperature （r = -0.169, -0.166, P = 0.083, 0.101). There was a positive correlation between CrSO2 and MAP (r = 0.287, P = 0.076), CrSO2 was negatively correlated with nose temperature, rectal temperature (r = -0.177, -0.180, P = 0.064, 0.097). There was no significant difference in PO2, blood lactate and urea nitrogen before and after systemic circulation after systemic circulation. There was no significant difference in PCO2, PO2, blood lactate and urea nitrogen between before systemic circulation, during systemic circulation, after systemic circulation (P > 0.05), comparison between any two means, the differences were not statistically significant (P > 0.05). Conclusion Renal oxygen saturation monitoring can be used as a new renal oxygenation monitoring application in infants with congenital heart disease surgery.

Key words： Renal oxygen saturation Infants Noncyanotic congenital heart disease

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	XIE Yuetao XING Dajun▲ YAO Cuicui MA Xinggang WANG Change

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XIE Yuetao XING Dajun▲ YAO Cuicui MA Xinggang WANG Change. Application and clinical significance of renal oxygen saturation monitoring in infants with noncyanotic congenital heart disease surgery[J]. 中国医药导报, 2018, 15(18): 154-157.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I18/154

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