血小板参数对急性心肌梗死患者急诊介入治疗后主要不良心脏事件的影响

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Abstract Objective To explore the relationship between platelet parameters and the incidence of major adverse cardiac events (MACE) in STEMI patients treated with percutaneous coronary intervention (PCI), and evaluate the predictive efficacy of each platelet parameter on MACE events. Methods From July 2013 to July 2017, the clinical data of 365 STEMI patients treated with primary PCI in the Daxing District People's Hospital were retrospectively analyzed. The date of MACE patient during the follow-up were recorded. According to the follow-up results, they were divided into two groups: MACE group (144 cases) and no MACE group (211 cases). The differences in baseline data and platelet parameters between the two groups were compared. Results There were significant differences between the two groups in age, hypertension history, platelet count, mean platelet volume and platelet distribution width (P < 0.05). Logistic regression analysis showed that MPV was independently associated with short-term MACE in acute STEMI after primary PCI (OR = 4.54, 95%CI: 1.11-18.47, P = 0.035). The sensitivity and specificity of MPV in predicting MACE were 72.9 % and 72.7%, respectively. Conclusion The increase in MPV is associated with recent MACE in STEMI patients after primary PCI and may be an independent predictor of the short-term prognosis of such patients.

Key words： ST segment elevation myocardial infarction Percutaneous coronary intervention Platelet parameters Major adverse cardiac events

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	WANG Wenbin JIAN Hongwei CHENG Guojie TANG Xuehong LI Xin

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WANG Wenbin JIAN Hongwei CHENG Guojie TANG Xuehong LI Xin. Effects of platelet parameters on incidence of major adverse cardiac events in patients with acute myocardial infarction after primary percutaneous interventional therapy[J]. 中国医药导报, 2018, 15(17): 48-51.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I17/48

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