新辅助化疗结合保肢手术治疗骨肉瘤26例

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Abstract Objective To explore the clinical efficacy of neoadjuvant chemotherapy combined with limb salvage surgery in the treatment of osteosarcoma. Methods From May 2012 to April 2014, 26 patients with limb osteosarcoma with limb salvage surgery in the First Affiliated Hospital of Guangxi University of Chinese Medicine were selected, and they were treated with preoperative and postoperative adjuvant chemotherapy. All the patients were followed up after discharge, and functional assessment of recovery was performed. Results During the follow-up period, 11 cases (42.31%) were evaluated to be excellent, while 7 cases (26.92%) were good according to the patient postoperative function, the excellent and good rate was 69.23% (18/26), the total effective rate was 88.46%. According to the survival curve, the 1,2,3 year disease-free survival rate after treatment were 92.3% (24/26), 74.1% (19/26) and 50.0% (13/26). Conclusion Neoadjuvant chemotherapy combined with limb salvage surgery is good for patients with osteosarcoma, which is worthy of clinical application.

Key words： Osteosarcoma Neoadjuvant chemotherapy Limb-salvage surgery

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	DU Mindong1 YI Shenghui2 QIN Gang1 HE Kaiyi1 HUANG Xiaohua1 ZENG Ping1 CHEN Jin1

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DU Mindong1 YI Shenghui2 QIN Gang1 HE Kaiyi1 HUANG Xiaohua1 ZENG Ping1 CHEN Jin1. Neoadjuvant chemotherapy combined with limb salvage surgery in treating 26 cases of osteosarcoma[J]. 中国医药导报, 2017, 14(29): 7-10.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2017/V14/I29/7

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