子宫内膜癌伴卵巢转移影响因素分析

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Abstract Objective To study the influence factor of ovarian metastasis in endometrial carcinoma. Methods 310 cases of patients with endometrial carcinoma who were first diagnosed and operatively treated in Xiangyang Central Hospital from June 2010 to June 2016 were retrospectively analyzed. Results 30 cases (9.7%) had ovarian metastasis in 310 cases of endometrial carcinoma. Single factor analysis showed that pathological type, histological grade, depth of myometrial invasion, vaginal invasion, fallopian tubes metastasis, lymph node metastasis, peritoneal fluid cytology, CA125 were significantly associated with ovarian metastasis (P < 0.05), while age, menopause, cervical invasion were not significantly associated with ovarian metastasis (P > 0.05). Multiple factors analysis showed that, independent risk factors of ovarian metastasis included positive peritoneal fluid cytology, higher CA125 level, positive lymph node metastasis, histological grade G2-G3, non-adenocarcinoma, positive fallopian tubes metastasis (P < 0.05). Conclusion Positive peritoneal fluid cytology, higher CA125 level, positive lymph node metastasis, histological grade G2-G3, non-adenocarcinoma, positive fallopian tubes metastasis are the independent predictive factors of ovarian metastasis in endometrial carcinoma. Ovarian preservation in patients with endometrial carcinoma is feasible, however, multi-center and larger sample research is necessary.

Key words： Endometrial carcinoma Ovarian Metatasis Risk factors

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	YANG Jing1 LEI Yuan1 XING Hui2

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YANG Jing1 LEI Yuan1 XING Hui2. Influence factor analysis of ovarian metastasis in endometrial carcinoma[J]. 中国医药导报, 2017, 14(14): 73-76.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2017/V14/I14/73

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