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| The value of serum lactic acid and its changes in prognosis assessment of patients with severe pulmonary infection |
| DU Baoqing |
| Department of Critical Care Medicine, Yantai Zhifu Hospital, Shandong Province, Yantai 264000, China |
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Abstract Objective To analyze the value of serum lactic acid and its changes in prognosis assessment of patients with severe pulmonary infection. Methods Clinical data of 100 cases of patients with severe pulmonary infection treated in Yantai Zhifu Hospital from February 2015 to March 2016 were analyzed retrospectively. According to the different criteria, patients were divided into different groups: ①according to the levels of blood lactate admitted in ICU, the patients were divided into hyperlactacidemia group (64 cases) and lactic acidosis group (36 cases). ②According to the value of 6 h blood lactate clearance rate, the patients were divided into high lactate clearance rate group (60 cases) and low lactate clearance rate group (40 cases). According to the prognosis, the patients were divided into survival group (79 cases) and death group (21 cases). The blood lactate levels of patients were detected, the prognosis was compared between different groups. Results Compared with lactic acidosis group, patients in hyperlactacidemia group had lower APACHEⅡ score, and higher 6 h lactate clearance rate, with statistically significant differences (P < 0.05). There were no significant differences in APACHEⅡ score and levels of blood lactate admitted in ICU between high lactate clearance rate group and low lactate clearance rate group (P > 0.05). There were no significant differences in APACHEⅡ score and levels of blood lactate admitted in ICU between survival group and death group (P > 0.05), but the 6 h blood lactate clearance rate of survival group was higher than that of control group, with statistically significant difference (P < 0.05). The mortality of hyperlactacidemia group was lower than that of lactic acidosis group, which of high lactate clearance rate group was lower than that of low lactate clearance rate group, with statistically significant differences (P < 0.05). Conclusion The level of blood lactic acid and 6 h lactic acid clearance rate can effectively reflect the severity of patients, while 6 h lactate clearance rate can also reflect the treatment effect of patients, the value in assessment is greater.
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