中药内服结合外敷气瘿穴治疗甲状腺良性结节的临床研究

Abstract
Figure/Table
References (20)
Related Citation (0)

Download: PDF (389 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract [Abstract] Objective To observe the clinical effect of oral Sanjie Ⅰ Prescription combined with local application of qi goiter acupoint in the treatment of benign thyroid nodules. Methods Eighty patients with benign thyroid nodules admitted to Zengcheng Hospital of Traditional Chinese Medicine in Guangzhou City from July 2014 to July 2015 were selected and randomly divided into two groups. 40 cases of the treatment group were taken oral Chinese medicine Sanjie Ⅰ Prescription combined with local application of Sanjie Ⅱ Prescription on bilateral qi goiter acupoint; 40 cases of the control group were taken oral Levothyroxine Tablets. The effects of two groups after treatment, the levels of thyroid hormones [thyroid stimulating hormone (TSH), serum free three iodine thyroid gland (FT3) and serum free thyroid hormone (FT4)] before and after treatment, the changes of the size of thyroid nodules and the changes of blood flow imaging in the nodules were observed. Results The total effective rate of treatment group was 92.5%, which of control group was 47.5%, the difference between the two groups was statistically significant (P ＜ 0.05). B ultrasound showed that the maximum diameter of the nodules [(9.23±4.52) mm] and the maximum cross-sectional area of the nodules [(65.53±55.42) mm2] were significantly decreased compared with the maximum diameter of the nodules [(12.36±4.68) mm] and the maximum cross section area [(75.66±52.08) mm2] of the control group, the differences were statistically significant (P ＜ 0.05). The levels of thyroid hormone (TSH, FT3, FT4) in the treatment group had no statistically significant differences compared with those before treatment (P ＞ 0.05). In the control group, the level of TSH after treatment [(0.73±0.34) mU/L] was decreased significantly compared with that before treatment [(1.96±0.79) mU/L] (P ＜ 0.05), the levels of FT3 [(3.95±2.33) pmol/L], FT4 [(13.95±2.61) pmol/L] after treatment were significantly increased compared with those before treatment [FT3: (3.52±1.06) pmol/L, FT4: (13.49±3.65) pmol/L] (P ＜ 0.05). There was a significant difference of blood flow classification after treatment between the two groups (P ＜ 0.05). Conclusion Oral medicinal herbs combined with external application of qi goiter acupoint in the treatment of benign thyroid nodules has a good effect, which is worthy of clinical promotion and application.

Key words： [Key words] Oral medicinal herbs Qi goiter acupoint Benign thyroid nodules

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	LIU Hongfang DIAO Weiqiang HU Xuhui ZHAO Jincheng CHEN Hao HUANG Yunshan ZENG Jianqiu CHEN Yuechao

Cite this article:

LIU Hongfang DIAO Weiqiang HU Xuhui ZHAO Jincheng CHEN Hao HUANG Yunshan ZENG Jianqiu CHEN Yuechao. Clinical study of oral medicinal herbs combined with external application of qi goiter acupoint in the treatment of benign thyroid nodules[J]. 中国医药导报, 2016, 13(3): 150-153.

URL:

http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2016/V13/I3/150

[参考文献]
[1] 熊专，孙晖，万姗，等.不同性质甲状腺结节临床特征的分析[J].中国实验诊断学，2014，43（4）：444-448.
[2] 中华医学会内分泌学分会，中华医学会外科学分会内分泌学组，中国抗癌协会头颈肿瘤专业委员会，中华医学会核医学分会.甲状腺结节和分化型甲状腺癌诊治指南[J].中国肿瘤临床，2012，39（17）：1249-1272.
[3] Levy MH，Back A，Benedetti C，et al. NNCN clinical practice guidelines in oncology v.2 [J]. Journal of the National Comprehensive Cancer Network Jnccn，2009，7（4）：436-473.
[4] 支颖川.从肝脾论治甲状腺结节[J].环球中医药，2015，8（2）：184-186.
[5] 上海市卫生局，中华医学会上海分会.外科诊疗常规[M].上海：上海科学技术出版社，2000.
[6] 国家中医药管理局.中医病证诊断疗效标准（外科）[M].北京：中国医药科技出版社，2012：3.
[7] 李荣，王子明.外科疾病诊断与疗效标准[M].上海：上海中医药大学出版社，2006：8.
[8] 石鹏，李星云，马彩叶，等.超声显示钙化灶对甲状腺良恶性结节的诊断意义[J].中华全科医学，2013，11（7）：1119-1120.
[9] 张彩芬，唐敏.滋阴理气散结法结合耳穴敷贴治疗单发性甲状腺结节190例[J].陕西中医，2015，36（6）：678-679.
[10] 任丁丁.甲状腺结节457例的临床病理分析[J].中国社区医师，2013，15（5）：239-240.
[11] 周广英，戚峰，陈曦，等.2844例甲状腺结节临床病理分析[J].中国中西医结合外科杂志，2013，19（3）：233-237.
[12] 郭健，张世豪，延丽雅，等.甲状腺结节的临床和病理特点分析[J].中国实用医药，2015，10（19）：14.
[13] 汪棪艳，张美丽，王玲飞.自拟消肿散结汤联合左甲状腺素钠片治疗甲状腺结节的临床观察[J].中国生化药物杂志，2015，35（7）：130-132.
[14] 马俊花，顾明君.甲状腺结节的诊断和治疗[J].上海医药，2015，36（7）：16-19.
[15] 王国霞.中西医结合治疗结节性甲状腺肿68例[J].河北中医，2014，36（11）：1651-1653.
[16] 黎涛.甲状腺结节综合药物治疗的临床效果分析[J].中国医药科学，2013，3（2）：64-65.
[17] 韩瑚，李俊贤，谢春光.扶正消瘿方辨治良性甲状腺结节临床体会[J].泸州医学院学报，2014，37（3）：315-317.
[18] 曲玉梅，周薇，孙桂明，等.软坚散结消瘿散治疗甲状腺结节临床观察[J].中国继续医学教育，2015，7（10）：254-255.
[19] 隋淼，刘超.“消肿散结片”治疗甲状腺结节40例临床研究[J].江苏中医药，2014，46（10）：36-37.
[20] 周鹏飞.甲状腺结节临床研究进展[J].中医学报，2013， 28（5）：733-735.