Correlation analysis between distribution features of tongue manifestations and some risk factors of the heart failure in dialysis patients
WANG Xiaolan1 XIAO Yonghua1 REN Chuanyun1 CAO Po1 LIU Yongguo2 YANG Shuming2 YIN Di1 ZHONG Jian1
1.Department of Nephrology and Endocrinology, Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing 100700, China;
2.Chinese Medicine Knowledge and Data Engineering Laboratory, Information and Software Engineering College, University of Electronic Science and Technology of China, Sichuan Province, Chengdu 610054, China
Abstract：Objective To investigate the correlation between the distribution of tongue image in patients with maintenance hemodialysis and some indices of the heart failure. Methods From August 2016 to April 2017, 77 cases of MHD patients (≥3 months) from Dongzhimen Hospital of Beijing University of Chinese Medicine and the First Integrated Traditional Chinese and Western Medicine Hospital were collected tongue information uniformly with the portable tongue image instrument. The tongue image was imported into the computer software "TCM expert system of tongue diagnosis". Three experts who are over deputy director of the physician level quantitated the 16 parameters of tongue image including the tongue spirit, the tongue color, the tongue shape, the teeth marks, cracks and etc to analyze MHD patients' distribution features of tongue manifestations; at the same time, the blood samples were took on the first day of tongue shooting, including blood routine, renal function, ion detection, serum albumin, BNP before hemodialysis, and the urea clearance index (Kt/V), the rate of urea decline (URR), the rate of interdialysis weight growth were calculated, then the correlation between tongue manifestations and objective indices was analyzed and the rules from it was found. Results Among the 77 patients undergoing maintenance hemodialysis, 41 cases were male and 36 cases were female. The score of teeth-marked tongue was positively associated with the rate of interdialysis weight growth (r = 0.488). The score of purple tongue, dark tongue, ecchymosis and thick coating were positively associated with BNP, which was positively correlated with congestion tongue (the value of r was in turn 0.532, 0.491, 0.525, 0.332, all P ＜ 0.01). Conclusion There is a positive correlation between the teeth-marked tongue and the rate of interdialysis weight growth in the maintenance hemodialysis patients. The congestion tongue is positively associated with the serum BNP. So the congestion tongue with teeth marks can be used as a reference for the hemodialysis patients with potential heart failure.
王小兰1 肖永华1 任传云1 曹钋1 刘勇国2 杨淑铭2 尹迪1 钟剑1. 透析患者舌象分布规律与部分心衰危险因素的相关性分析[J]. 中国医药导报, 2018, 15(10): 110-113.
WANG Xiaolan1 XIAO Yonghua1 REN Chuanyun1 CAO Po1 LIU Yongguo2 YANG Shuming2 YIN Di1 ZHONG Jian1. Correlation analysis between distribution features of tongue manifestations and some risk factors of the heart failure in dialysis patients. 中国医药导报, 2018, 15(10): 110-113.
2018, Vol. 15 
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