Abstract：Objective To discuss the possibility and safety of video-assisted thoracoscope surgery (VATS) for pulmonary aspergilloma and the postoperative stress reaction. Methods The clinical data of 66 patients with pulmonary aspergilloma in People′s Hospital of Hainan Province from February 2011 to September 2016 were retrospectively analyzed. The patients were divided into two groups according to their operation method including a conventional thoracotomy surgery group (open group, n = 36) and a video-assisted thoracoscope pneumonectomy group (VATS group, n = 30). The clinical data, complications, NPS and stress reaction-related indicators of the two groups were observed after surgery. Results The operations of all patients were performed successfully. The VATS group was significantly lower than the open group in the operation time, bleeding, total postoperative drainage, the 7th day pain score and the 30th day pain score (P < 0.05). There were no statistical differences in the time of hospitalization, the 1st day pain score and postoperation complication (P > 0.05). In stress response indexes (cortisol, prostaglandin E2 and P substance), the postoperative levels of 1st day and 7th day in the VATS group were significantly lower than those in the open group (P < 0.05). In inflammatory reaction indexes (C-reactive protein, interleukin 6 and tumor necrosis factor-α), the postoperative levels of 1st day and 7th day in the VATS group were significantly lower than those in the open group (P < 0.05). Conclusion VATS for pulmonary aspergilloma, if applicable, may be reliable therapeutic effect, and less impact on the postoperative stress reaction. It is worthy of clinical application.
蔡仁中 陈献珊 陈锋夏. 胸腔镜手术治疗肺曲霉病的效果和术后应激反应情况[J]. 中国医药导报, 2018, 15(10): 63-67.
CAI Renzhong CHEN Xianshan CHEN Fengxia . Clinical effect of thoracoscopic surgery for patients with pulmonary aspergilloma and the influence on the postoperative stress reaction. 中国医药导报, 2018, 15(10): 63-67.
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2018, Vol. 15 
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