Abstract：Rhodiola is a rare wild medicinal material.Salidroside is the main effective component of Rhodiola and has significant anti-aging and anti-oxidant pharmacological effects. After reviewing and summarizing the recent 3-year relative research at home and abroad, we found that studies mainly involved nervous system, cardiovascular system, skin and other aspects. The specific pharmacological mechanisms involved PI3K/Akt/GSK-3β,PI3K/Akt/Nrf2/HO-1, SIRT1/NF-κB, cAMP/PKA/CREB, NOX2/ROS/MAPKs, autophagy and so on. In conclusion, this review is of great significance for researchers who try to further research pharmacological mechanisms of salidroside and take use of targeted pathways to develop new drugs.
李慧 孙乐栋. 红景天苷抗衰老和抗氧化药理机制研究新进展[J]. 中国医药导报, 2018, 15(7): 51-54,81.
LI Hui SUN Ledong. Recent research progress on the pharmacological mechanisms of anti-aging and anti-oxidation by salidroside. 中国医药导报, 2018, 15(7): 51-54,81.
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2018, Vol. 15 
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