Effect of laparoscopic salpingectomy on serum β-HCG, blood routine and C-reactive protein levels and reproductive outcome in patients with ectopic pregnancy
XIE Wei YU Min▲
Department of Obstetrics and Gynecology, the 901 Hospital of the Joint Logistic Support Force of the People’s Liberation Army, Anhui Province, Hefei 230031, China
Abstract：Objective To study the effect of laparoscopic salpingectomy on serum β-human chorionic gonadotropin (β-HCG), blood routine and C-reactive protein levels and reproductive outcome in patients with ectopic pregnancy. Methods A total of 110 cases of ectopic pregnancy admitted by the 901 Hospital of the Joint Logistic Support Force of the People’s Liberation Army from September 2017 to September 2020 were selected as study objects. According to the random number table method, they were divided into study group and control group, with 55 cases in each group. Study group was treated with laparoscopic salpingectomy, and control group was treated with ectopic pregnancy drug embryo killing conservative treatment. The serum β-HCG level, the decreasing extent of serum β-HCG level, the time taken for serum β-HCG level to return to normal level, hospital stay, reproductive outcome (ovulation rate, pregnancy rate, ectopic pregnancy rate), blood routine and C-reactive protein were compared between two groups. Results Before treatment, there was no significant difference in serum β-HCG level between two groups (P > 0.05). After 72 h of treatment, serum β-HCG level in both groups were lower than those before treatment, and study group was lower than control group, and the differences were all highly statistically significant (all P < 0.01). After 72 h of treatment, the decreasing extent of serum β-HCG level in study group was greater than that in control group, and the time taken for serum β-HCG level to return to normal level was shorter than that in control group; hospital stay of study group was shorter than that of control group, and the differences were highly statistically significant (all P < 0.01). There were no significant differences in ovulation rate and ectopic pregnancy rate between two groups after treatment (P > 0.05). The pregnancy rate in study group was higher than that in control group, and the difference was statistically significant (P < 0.05). There were no significant differences in blood routine and C-reactive protein between two groups (P > 0.05). Conclusion Laparoscopic salpingectomy in the treatment of ectopic pregnancy has significant curative effect, which is conducive to the recovery of serum β-HCG level, improving postoperative pregnancy rate of patients, shortening the hospital stay, no infection after operation, good recovery and high safety. It has clinical application value and is worthy of promotion.
2021, Vol. 18 
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