Research progress on LncRNA MALAT1 and breast cancer
WANG Simin1 LI Na1 XIONG Haojun1 ZHANG Cuiwei2 CHAI Li2▲
1.Clinical Medicine College, Southwest Medical University, Sichuan Province, Luzhou 646000, China;
2.Department of Pathology, the Affiliated Hospital of Southwest Medical University, Sichuan Province, Luzhou 646000, China
Abstract:Breast cancer is one of the most common female malignant tumors in China. In recent years, the occurrence and development of non-coding RNA in the breast cancer has attracted increasingly attention. MALAT1 is a long non-coding RNA closely related to the proliferation, invasion, metastasis and prognosis of breast cancer. However, its role in various stages of breast cancer is still controversial, and its molecular mechanism is still unclear. This paper summarizes the research progress of LncRNA MALAT1 in breast cancer, aiming to provide new ideas for the early detection and diagnosis of breast cancer, and to explore new drug targets.
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