自体月经血来源干细胞治疗宫腔粘连的研究进展
马海兰1 刘梦婷2 王巍1▲
1.广西壮族自治区桂平市人民医院生殖医学中心,广西桂平 537200;
2.武汉汉密顿生物科技股份有限公司,湖北武汉 430040
Research progress of autologous menstrual blood derived stem cells in the treatment of intrauterine adhesions
MA Hailan1 LIU Mengting2 WANG Wei1▲
1.Reproductive Medicine Center, Guiping People’s Hospital, Zhuang Automous Region, Guiping 537200, China;
2.Wuhan Hamilton Biotechnology Co.,Ltd.,Hubei Province,Wuhan 430040, China
摘要 宫腔粘连属于一种常见子宫内膜损伤性疾病。加之,宫腔粘连的发生与子宫内膜干细胞减少及功能缺陷有关,故干细胞移植为治疗宫腔粘连提供了全新的可能。因此,如何治疗宫腔粘连、预防粘连再发生、解决患者妊娠需求是目前临床亟需解决的问题之一。其中月经血干细胞因具有增殖快、可多次取样、无创伤、无伦理问题等优点而被广泛研究。本文就近年来自体月经血干细胞治疗宫腔粘连的前景做一综述,为治疗宫腔粘连提供新的思路。
关键词 :
月经血干细胞 ,
子宫内膜 ,
宫腔粘连 ,
不孕
Abstract :The intrauterine adhesions are a kind of common endometrial injury diseases. In addition, the occurrence of intrauterine adhesions is related to the decrease of endometrial stem cells and functional defects, so stem cell transplantation provides a new possibility for the treatment of intrauterine adhesions. Therefore, how to treat intrauterine adhesions, prevent the recurrence of adhesions, and solve the pregnancy needs of patients is one of the urgent clinical problems. Among them, menstrual blood stem cells have been widely studied for their advantages such as rapid proliferation, multiple sampling, non-trauma, and no ethical issues and so on. This article reviews the prospect of autologous menstrual blood stem cells in the treatment of intrauterine adhesions in recent years, and provides a new idea for the treatment of intrauterine adhesions.
Key words :
Menstrual blood stem cells
Endometrium
Intrauterine adhesions
Infertility
基金资助: 广西壮族自治区卫生健康委员会自筹经费科研课题(Z20190130)。
通讯作者:
▲通讯作者
作者简介 : 马海兰(1967-),女,主任医师;研究方向:生殖医学临床。
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