Prescription rules analysis of Professor Zheng Huifang in treating metrorrhagia based on data mining
BI Yingxue1 HE Jing1 ZHENG Saisai2 ZHAO Ping2 SUI Xinyue1 LIU Hui3
1.College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Shandong Province, Ji’nan 250014, China;
2.the First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Shandong Province, Ji’nan 250014, China;
3.Department of Gynecology, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Shandong Province, Ji’nan 250014, China
Abstract：Objective To explore the prescription and medication rules of Professor Zheng Huifang of national famous veteran Chinese medicine practitioners in the treatment of metrorrhagia through data mining. Methods The prescriptions of metrorrhagia diagnosed by Professor Zheng Huifang in the papers, books and medical records published in the past clinical teaching and scientific research were collected. And the standard data was entered into the traditional Chinese medicine inheritance support system, the corresponding database was established by using the platform, and the data was counted and analyzed. Results A total of 63 medical records of Professor Zheng Huifang were collected, including 271 prescriptions. According to the analysis, the high-frequency drugs were Radix Rehmannia Preparata, Radix Astragali seu Hedysari, liquorice root, Os Draconis, Rhizoma Atractylodis Macrocephala, ass hide glue, Fructus Schisandrae Chinensis, Herba Ecliptae, Fructus Corni and Radix Paeoniae Alba. According to the efficacy of traditional Chinese medicine, qi tonic, yin tonic, blood tonic and astringent drugs were more common. Through the analysis of the four qi and five flavors of traditional Chinese medicine, the drugs used were warm, mild, sweet, bitter and pungent. According to the analysis of the meridian tropism of drugs, the drugs of liver meridian were the most commonly used, followed by the drugs of kidney and spleen meridians. Through cluster analysis, three new combinations were obtained: Oyster shall, Os Draconis, Radix Angelicae Sinensis, Poria, Rhizoma Cimicifugae; Cornus officinalis, Rhizoma Dioscoreae, Radix Rehmanniae Preparata, sanqi; eucommia, ass hide glue, Rhizoma Atractylodis macrocephala, Schizonepeta tenuifolia, coix seed. Conclusion Through data mining, Professor Zheng Huifang in the treatment of metrorrhagia is mainly based on nourishing the spleen, kidney and liver, pay attention to the sweet and warm drugs in medication. The new prescription obtained through analysis needs to be further verified by clinicians. Through the analysis, it also provides the direction for the better application of traditional Chinese medicine in the clinical treatment of metrorrhagia.
毕映雪1 何静1 郑赛赛2 赵萍2 隋新月1 刘卉3. 基于数据挖掘分析郑惠芳教授治疗崩漏的组方规律[J]. 中国医药导报, 2021, 18(3): 164-167.
BI Yingxue1 HE Jing1 ZHENG Saisai2 ZHAO Ping2 SUI Xinyue1 LIU Hui3. Prescription rules analysis of Professor Zheng Huifang in treating metrorrhagia based on data mining. 中国医药导报, 2021, 18(3): 164-167.
2021, Vol. 18 
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