Exploration on the medication rules of the treatment of tremor syndrome in ancient literatures based on data mining method
CHEN Xinjie1 ZHENG Chunying1 LUO Xiaodong2 LUO Enli2 SU Qiaozhen2 ZHENG Chunye2
1.The Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangdong Province, Guangzhou 510405, China;
2.Department of Neurology, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Province, Guangzhou 510120, China
Abstract：Objective To find the rules of ancient documents of traditional Chinese medicine in the treatment of tremor syndrome with data mining method. Methods Based on the data of Chinese Medical Canon and Guangzhou University of Chinese Medicine and the library of Guangdong Provincial Hospital of Traditional Chinese Medicine, the database of diagnosis and treatment of tremor syndrome in ancient books was established. The ancient and modern medical case cloud platform V1.7 was used. Frequency statistics, clustering analysis, association rules, complex network and other data mining technologies were used for analysis. Results A total of 177 prescriptions were included, involving 264 kinds of drugs. Its main properties were warm, sweet, and mainly belong to liver, spleen, lung meridian. The common herb pairs included “Angelicae Sinensis Radix-Ginseng Radix et Rhizoma”, “Astragali Radix-Ginseng Radix et Rhizoma”, “Schisandrae Chinensis Fructus”, and so on. High frequency drugs included Poria, Ginseng Radix et Rhizoma, Glycyrrhizae Radix et Rhizoma Praeparata Cum Melle, Atractylodis Macrocephalae Rhizoma, Angelicae Sinensis Radix, and so on. Combined with cluster analysis and complex network analysis, the core drug combination can be considered as Bazhen Decoction, Tianma Gouteng Decoction and Dihuang Yinzi. Conclusion The treatment of tremor syndrome in ancient documents of traditional Chinese medicine usually start from treatments of liver and spleen and mainly focus on usages of warm drugs. The common function of prescription for tremor syndrome in ancient documents include the effects of invigorating spleen and benefiting qi, suppressing hyperactive liver for claming endogenous wind, relieving muscle stiffness and pain, nourishing blood and reinforcing deficiency.
陈信捷1 郑春莹1 雒晓东2 罗恩丽2 苏巧珍2 郑春叶2. 基于数据挖掘法探究古籍文献治疗颤证用药规律[J]. 中国医药导报, 2020, 17(36): 135-138，154.
CHEN Xinjie1 ZHENG Chunying1 LUO Xiaodong2 LUO Enli2 SU Qiaozhen2 ZHENG Chunye2. Exploration on the medication rules of the treatment of tremor syndrome in ancient literatures based on data mining method. 中国医药导报, 2020, 17(36): 135-138，154.
2020, Vol. 17 
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