Abstract：Objective To explore the clinical role of monitoring of oxygenation index (OI) and Alveolar arterial oxygen partial pressure difference (A-aDO2) for children with severe pneumonia. Methods The clinical data of 71 children with severe pneumonia who had been seeking treatment in the Affiliated Hospital of Inner Mongolia Medical University from March 2016 and March 2017 were set as the study group, and according to the acute physiology and chronic health evaluation (APACHE-Ⅱ) scores, these patients were divided into study group A (≥40 points), the study group B (20 -＜40 points) and study group C (<20 points). Another 71 healthy children were selected during the same period as the control group. Blood gas monitoring was carried in all the three groups. The OI/endothelial surface area, A-aDO2/endothelial surface area at difference time periods, and prognosis in the three study groups were compared. Results The OI/endothelial surface area was registered at in study group A, in study group B and in study group C, all lower than the control group, and the study group A was the lowest, where the differences were statistically significant (P < 0.01). The A-aDO2/endothelial surface area in study group A, study group B, and study group C were higher than that in the control group, and the study group A was the highest (P ＜ 0.01). The OI/endothelial surface area increased over the treatment time, whereas the A-aDO2/endothelial surface area decreased over the treatment time. All of the above differences were statistically significant (P < 0.01). Out of the 71 cases of children with severe pneumonia, 70 cases survived and 1 died. Conclusion For children with severe pneumonia, dynamic monitoring of OI and A-aDO2 can assess their conditions, thus providing guidance for its clinical treatment and prognosis improvement. Therefore, it is of significant value to be popularized in clinical application.
杨轶男 王海燕 朝鲁门其其格. 氧合指数及肺泡动脉氧分压差监测对小儿重症肺炎的临床价值分析[J]. 中国医药导报, 2018, 15(1): 72-75.
YANG Yi′nan WANG Haiyan Chaolumen Qiqige. Clinical role of monitoring of oxygenation index and alveolar arterial oxygen partial pressure difference in children with severe pneumonia. 中国医药导报, 2018, 15(1): 72-75.
2018, Vol. 15 
京公网安备 11010502046598号