Advances in the pharmacological action and clinical application of Kunxian Capsules in the treatment of immunological kidney diseases
DENG Yi1* ZHU Dekang1,2* TAO Xia1 ZHANG Feng1 CHEN Wansheng1,3
1.Department of Pharmacy, Changzheng Hospital, the Second Military Medical University, Shanghai 200003, China;
2.Academic Affairs Office of Naval Medical University, Shanghai 200433, China;
3.Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
Abstract:Kunxian Capsules is composed of tripterygium hypoglaucum, epimedium herb, barbary wolfberry fruit and dodder seed, has the effect of tonifying kidney and dredging channels, dispelling wind and eliminating dampness, and also has anti-inflammatory, immunosuppressive and improving kidney function. It is a commonly used drug in clinical treatment of rheumatoid arthritis and other immune diseases. The study of Kunxian Capsules in immunological kidney diseases has attracted increasing attention, focusing on the combination of Kunxian Capsules with hormones and immunosuppressive/cytotoxic drugs to protect kidney function and reduce adverse reactions. In this paper, the pharmacological action and clinical research progress of Kunxian Capsules in the treatment of immunological kidney diseases are reviewed in order to provide references for rational clinical use of drugs.
邓易1* 朱德康1,2* 陶霞1 张凤1 陈万生1,3. 昆仙胶囊治疗免疫性肾脏类疾病的药理作用及临床应用进展[J]. 中国医药导报, 2020, 17(27): 48-50,61.
DENG Yi1* ZHU Dekang1,2* TAO Xia1 ZHANG Feng1 CHEN Wansheng1,3. Advances in the pharmacological action and clinical application of Kunxian Capsules in the treatment of immunological kidney diseases. 中国医药导报, 2020, 17(27): 48-50,61.