Abstract：Objective To observe the effect of laparoscopic radical prostatectomy in the treatment of prostate cancer and its effect on bladder function. Methods A total of 96 patients with prostate cancer who were treated in the Second People′s Hospital of Wuhu, Anhui Province from February 2016 to January 2019 were selected as the research objects, and were divided into laparoscopic group and open group according to the surgical method, with 48 patients in each group. The differences of operation general condition, bladder function, quality of life, complication rate and recurrence rate were compared between the two groups. Results The intraoperative blood loss in the laparoscopic group was significantly lower than that in the open group, and the difference was statistically significant (P ＜ 0.05). There was no significant difference in operation time between the two groups (P ＞ 0.05). Six months after the operation, the international scores of prostate symptoms in both groups were lower than three months after surgery, and the differences were statistically significant (all P ＜ 0.05). Six months after the operation, the maximum urine flow rate of both groups was higher than that of the three months after surgery, and the laparoscopy group was higher than the open group, with statistically significant differences (all P ＜ 0.05). There was no statistically significant difference in the quality of life between the two groups before the operation (P ＞ 0.05). Six months after the operation, the scores of physical function, physical role, overall health, vitality, social function, emotional role and mental health in the open group were higher than those before the operation, with statistically significant differences (all P ＜ 0.05). But the differences in the physical pain scores were not statistically significant compared with those before the operation (P ＞ 0.05). All the life quality scores of the laparoscopic group were improved compared with those before the operation, and all the life quality scores of the laparoscopic group were higher than those of the open group, with statistically significant differences (all P ＜ 0.05). There were no significant differences in postoperative complication rate and recurrence rate between the two groups (P ＞ 0.05). Conclusion Laparoscopic radical prostatectomy has a low operative blood loss, little influence on the urine function of patients, low incidence of complications, and has a good application value.
石结武 陶凌松 徐磊 丁维. 腹腔镜下前列腺癌根治术治疗前列腺癌患者的效果及对膀胱功能的影响[J]. 中国医药导报, 2020, 17(26): 99-103.
SHI Jiewu TAO Lingsong XU Lei DING Wei. Effect of laparoscopic radical prostatectomy in the treatment of prostate cancer and its effect on bladder function. 中国医药导报, 2020, 17(26): 99-103.
2020, Vol. 17 
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