Application of CT-guided coaxial needle biopsy in early qualitative diagnosis of pulmonary nodules
YE Xiaocong1,2 CHEN Qizhong1 HAO Mingzhi1 LIN Hailan1
1.Department of Interventional Therapy, Fujian Provincial Cancer Hospital Fujian Medical University Cancer Hospital, Fujian Province, Fuzhou 350014, China; 2.Department of Surgery, Fujian Changtai County Hospital, Fujian Province, Zhangzhou 363000, China
Abstract：Objective To explore the application value and safety of CT-guided coaxial needle biopsy in the early qualitative diagnosis of pulmonary nodules. Methods A total of 122 patients with pulmonary nodules (≤3 cm) admitted to Fujian Provincial Cancer Hospital from January to December 2017 who underwent percutaneous biopsy with CT-guided coaxial needle biopsy were retrospectively analyzed. The efficacy and safety of this technique were evaluated through the analysis of puncture success rate, incidence of complications and related influencing factors. Results The puncture biopsy was successfully performed in 121 cases (99.18%), among them, 92 cases (75.4%) were malignant tumors, and the puncture was terminated in one case due to pneumothorax compression more than 20%. Among 122 cases, pneumothorax was found in 11 cases (9.02%). Three patients with lung compression more than 20% (2.5%) were improved by self-absorption after observation (without drainage). There were 14 cases of concurrent hemorrhage (11.5%), including one case (0.8%) of hemoptysis, which was improved after hemostasis treatment. There was no gas embolism and no needle implantation occurred in the follow-up period of two years. Pneumothorax was related to emphysema and obstructive pneumonia after pulmonary nodule puncture of patients (all P ＜ 0.05). Hemorrhage after puncture was related to the size of emphysema and pulmonary nodules (all P ＜ 0.05). Conclusion CT-guided coaxial needle biopsy has higher application value and safety in the early qualitative diagnosis of pulmonary nodules.
2020, Vol. 17 
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