Prognostic value of red blood cell volume distribution width in patients with acute decompensated heart failure with preserved ejection fraction
GUO Qinghong1 TANG Long2 FENG Qifan2 XI Xiaotu3
1.Department of Emergency, People′s Hospital of Xuancheng City, Anhui Province, Xuancheng 242000, China;
2.Department of Cardiology, People′s Hospital of Xuancheng City, Anhui Province, Xuancheng 242000, China;
3.Department of Emergency, Guangdong Hospital of Traditional Chinese Medicine, Guangdong Province, Guangzhou 510000, China
Abstract：Objective To explore prognostic value of red blood cell distribution width (RDW) in patients with acute decompensated heart failure with preserved ejection fraction (HFpEF). Methods One hundred and twenty-nine patients with acute decompensated HFpEF admitted to People′s Hospital of Xuancheng City from January 2014 to December 2018 were selected. RDW level on admission was measured and followed up for 12 months. Patients were divided into good prognosis group and poor prognosis group according to the death and re-hospitalization of acute heart failure during the follow-up period. Clinical baseline of two groups was compared, and the value of RDW in predicting the prognosis of acute decompensated HFpEF patients was analyzed by receiver operating characteristic (ROC) curve. Results One hundred and twenty-one patients were followed up, 37 cases in poor prognosis and 84 cases in good prognosis. The age, the proportion of essential hypertension, the proportion of diabetes, atrial fibrillation, New York Heart Disease Association (NYHA) grade, creatinine, alanine aminotransferase, troponin I and RDW levels between two groups were compared, the differences were statistically significant (P < 0.05). Multiple logistic regression analysis showed that the history of atrial fibrillation (OR = 1.865, 95%CI: 1.325-12.592), NYHA grade (OR = 1.536, 95%CI: 1.205-10.628) and RDW (OR = 2.298, 95%CI: 1.406-16.274) were related to the poor prognosis of acute decompensated HFpEF (all P ＜ 0.01). ROC analysis results showed that RDW predicted acute decompensated HFpEF prognosis with the best cut-off value of 15%, the area under the curve was 0.724, the sensitivity was 72.97%, and the specificity was 66.67%. Conclusion The rise of RDW is closely related to the poor prognosis of acute decompensated HFpEF patients. RDW can be used as an auxiliary index to predict the prognosis of acute decompensated HFpEF patients.
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2020, Vol. 17 
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