Clinical effect of Xiaoyao Powder addition and subtraction combined with Escitalopram Oxalate in the treatment of elderly patients with post-stroke depression and liver-depression type of fire
ZHAO Shichu1 LU Yanli1 TIAN Zhijun1 SONG Qingyang2
1.Department of Medical, Beijing Longfu Hospital, Beijing 100010, China;
2.Department of Geriatrics, Beijing Longfu Hospital, Beijing 100010, China
Abstract：Objective To investigate the clinical effect of Xiaoyao Powder addition and subtraction combined with Escitalopram Oxalate on depressive psychology and daily life ability in the elderly patients with post-stroke depression. Methods A total of 138 elderly patients with post-stroke depression in Beijing Longfu Hospital from February 2018 to November 2019 were selected and divided into the observation group and the control group according to the random number table method, with 69 patients in each group. The control group was treated with Escitalopram Oxalate only, while the observation group was treated with the combination of traditional Chinese and Western medicine treatment with Xiaoyao Powder addition and subtraction combined with Escitalopram Oxalate. After two courses (8 weeks) of treatment, the improvement of depression status, cognitive ability, life ability and social function of patients in the two groups were compared. Results After treatment, the Hamilton depression scale score in the observation group was lower than that of the control group, and the difference was statistically significant (P ＜ 0.05). The score of mini-mental state examination and the Barthel index of activity daily living in the observation group were higher than those in the control group, and the differences were statistically significant (all P ＜ 0.05). The comparison of functional activities questionnaire between the two groups showed no statistically significant difference (P ＞ 0.05). Conclusion The combination of traditional Chinese and Western medicine treatment with Xiaoyao Powder addition and subtraction combined with Escitalopram Oxalate in the elderly stroke patients is more effective in alleviating patients′ depression, improving their mental state and enhancing their activity daily living than the single use of Escitalopram Oxalate.
赵世初1 卢艳丽1 田志军1 宋清扬2. 逍遥散加减联合草酸艾司西酞普兰治疗老年脑卒中后抑郁肝郁化火型患者的临床效果[J]. 中国医药导报, 2020, 17(20): 97-100.
ZHAO Shichu1 LU Yanli1 TIAN Zhijun1 SONG Qingyang2. Clinical effect of Xiaoyao Powder addition and subtraction combined with Escitalopram Oxalate in the treatment of elderly patients with post-stroke depression and liver-depression type of fire. 中国医药导报, 2020, 17(20): 97-100.
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2020, Vol. 17 
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